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Case Reports
. 2022 May;48(5):1265-1270.
doi: 10.1111/jog.15195. Epub 2022 Feb 16.

Pregnancy-induced hemorrhagic degeneration of adenomyosis

Megumi Nakanishi  1 , Takayuki Iriyama  1 , Seisuke Sayama  1 , Shouhei Hanaoka  2 , Masatake Toshimitsu  1 , Takahiro Seyama  1 , Kenbun Sone  1 , Keiichi Kumasawa  1 , Takeshi Nagamatsu  1 , Yutaka Osuga  1
Affiliations
Case Reports

Pregnancy-induced hemorrhagic degeneration of adenomyosis

Megumi Nakanishi et al. J Obstet Gynaecol Res. 2022 May.

Abstract

Uterine fibroids are known to degenerate during pregnancy, but it is unknown if similar pathologic condition occurs in adenomyosis. A 38-year-old para 1 woman exhibited uterine tenderness and a markedly elevated inflammatory response at 22 weeks of gestation. Based on magnetic resonance imaging (MRI) findings indicative of hemorrhagic components in an adenomyosis lesion, we judged these features resulted from degeneration of adenomyosis after excluding the possibility of underlying infection by amniocentesis. Although these symptoms improved with conservative management, nonreassuring fetal status prompted an emergency cesarean section at 27 weeks of gestation. MRI performed 4 months postpartum revealed the degeneration had completely disappeared. The present case confirms the presence of a pathologic condition-transient degeneration in adenomyosis-which is triggered by pregnancy.

Keywords: adenomyosis; amniocentesis; pregnancy.

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References

    1. Kim SH, Kim JK, Chae HD, Kim CH, Kang BM. Rapidly growing adenomyosis during the first trimester: magnetic resonance images. Fertil Steril. 2006;85(4):1057-8.
    1. Parazzini F, Tozzi L, Bianchi S. Pregnancy outcome and uterine fibroids. Best Pract Res Clin Obstet Gynaecol. 2016;34:74-84.
    1. Hirashima H, Ohkuchi A, Usui R, Kijima S, Matsubara S. Magnetic resonance imaging of degeneration of uterine adenomyosis during pregnancy and post-partum period. J Obstet Gynaecol Res. 2018;44(6):1169-73.
    1. Kim SC, Lee NK, Yun KY, Joo JK, Suh DS, Kim KH. A rapidly growing adenomyosis associated with preterm delivery and postpartum abscess formation. Taiwan J Obstet Gynecol. 2016;55(4):620-2.
    1. Zhang J, Xiao X, Luo F, Shi G, He Y, Yao Y, et al. Acute disseminated intravascular coagulation developed after dilation and curettage in an adenomyosis patient: a case report. Blood Coagul Fibrinolysis. 2013;24(7):771-3.

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