Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Jan 24:13:786712.
doi: 10.3389/fphar.2022.786712. eCollection 2022.

Syzygium jambos L. Alston: An Insight Into its Phytochemistry, Traditional Uses, and Pharmacological Properties

Melvin Adhiambo Ochieng  1   2 , Widad Ben Bakrim  2   3 , Gabin Thierry M Bitchagno  2 , Mona F Mahmoud  4 , Mansour Sobeh  2
Affiliations
Review

Syzygium jambos L. Alston: An Insight Into its Phytochemistry, Traditional Uses, and Pharmacological Properties

Melvin Adhiambo Ochieng et al. Front Pharmacol. .

Abstract

Medicinal plants have been used since ancient times for human healthcare as drugs, spices, and food additives. The progress in technology and medicine observed, the last decades, has improved the quality of life and healthcare but with worrisome drawbacks. Side effects caused by synthetic drugs for instance originate sometimes irreversible health disorders. Natural substances, in contrast, are biologically and environmentally friendly. Syzygium jambos L. (Alston) also known as rose apple conveys a long history as essential traditional medicine with a broad spectrum of application in various cultures. The plant discloses a diverse group of secondary metabolites and extracts that displayed major susceptibilities towards various health concerns especially stress-related and inflammatory diseases. Despite a rich literature about the plant, the chemistry and biology of S. jambos have not been comprehensively reviewed yet. Accordingly, we present herein a literature survey of rose apple which aims to draw the chemical identity of the plant and establish a consistent discussion on the respective biological application of plant extracts and their corresponding traditional uses. The present work could provide a scientific basis for future studies and necessary information for further investigations of new drug discovery.

Keywords: Syzygium jambos; antiinflammatory; antioxidant; medicinal plants; pharmacological activities.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Syzygium jambos (A) tree, (B) flowers, (C) unripe fruits and (D) seeds.
FIGURE 2
FIGURE 2
Selected secondary metabolites from S. jambos.
FIGURE 3
FIGURE 3
Biological activities of S. jambos.
See this image and copyright information in PMC

References

    1. Abad M. J., Bermejo P., Villar A., Sanchez Palomino S., Carrasco L. (1997). Antiviral Activity of Medicinal Plant Extracts. Phytother. Res. 11 (3), 198–202. 10.1002/(sici)1099-1573(199705)11:3<198:aid-ptr78>3.0.co;2-l - DOI
    1. Apaza Ticona L., Souto Pérez B., Martín Alejano V., Slowing K. (2021). Anti-inflammatory and Anti-arthritic Activities of Glycosylated Flavonoids from Syzygium Jambos in Edematogenic Agent-Induced Paw Edema in Mice. Rev. Bras. Farmacogn. 31 (4), 429–441. 10.1007/s43450-021-00167-0 - DOI
    1. Athikomkulchai S., Lipipun V., Leelawittayanont T., Khanboon A., Ruangrungsi N. (2008). Anti-herpes Simplex Virus Activity of Syzygium Jambos. J. Health Res. 22 (1), 49–51.
    1. Ávila-Peña D., Peña N., Quintero L., Suárez-Roca H. (2007). Antinociceptive Activity of Syzygium Jambos Leaves Extract on Rats. J. Ethnopharmacology 112 (2), 380–385. 10.1016/j.jep.2007.03.027 - DOI - PubMed
    1. Baliga M. S., Ranganath Pai K. S., Saldanha E., Ratnu V. S., Priya R., Adnan M., et al. (2017). “Rose Apple (Syzygium Jambos (L.) Alston),” in Fruit and Vegetable Phytochemicals: Chemistry and Human Health. Editor Yahia E. M.. Second Edition 2 (Hoboken, NJ, USA: John Wiley and Sons; ), 1235–1242.

LinkOut - more resources