Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Feb;26(3):1004-1016.
doi: 10.26355/eurrev_202202_28009.

Predictive factors for lymph node involvement in sporadic medullary thyroid microcarcinoma: a systematic review

G Scerrino  1 , G Cocorullo, G Orlando, G Rotolo, A Corigliano, C Amato, M P Proclamà, I Vitale, G Melfa, N C Paladino
Affiliations
Free article

Predictive factors for lymph node involvement in sporadic medullary thyroid microcarcinoma: a systematic review

G Scerrino et al. Eur Rev Med Pharmacol Sci. 2022 Feb.
Free article

Abstract

Objective: The aim of the study was to determine the impact of laboratory and imaging tests in predicting central and lateral neck lymph node/LN involvement and in decision making for surgical extent.

Materials and methods: A PubMed, Web of Science and Scopus search was performed according to PRISMA criteria. The relationship between nodule size, diagnostic biomarkers and imaging with LN involvement were evaluated.

Results: The available data analysis did not yield clear indications of the relationship between each of these topics and the presence, number, and location of LN involved. There was no conclusive data for the selective indication of central neck dissection in the preoperative diagnosis of microMTC.

Conclusions: There is no justification for less invasive interventions than total thyroidectomy with lymph node dissection.

PubMed Disclaimer

Publication types