Recognition of observer effect is required for rigor and reproducibility of preclinical animal studies

Affiliations

¹ Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: chi-ping.day@nih.gov.
² Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
³ Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
⁴ Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: gmerlino@helix.nih.gov.

Free article

Comment

Chi-Ping Day et al. Cancer Cell. 2022.

Free article

. 2022 Mar 14;40(3):231-232.

doi: 10.1016/j.ccell.2022.01.015. Epub 2022 Feb 17.

¹ Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: chi-ping.day@nih.gov.
² Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
³ Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
⁴ Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: gmerlino@helix.nih.gov.

No abstract available

Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Elimination of fluorescent protein immunogenicity permits modeling of metastasis in immune-competent settings.
Grzelak CA, Goddard ET, Lederer EE, Rajaram K, Dai J, Shor RE, Lim AR, Kim J, Beronja S, Funnell APW, Ghajar CM. Grzelak CA, et al. Cancer Cell. 2022 Jan 10;40(1):1-2. doi: 10.1016/j.ccell.2021.11.004. Epub 2021 Dec 2. Cancer Cell. 2022. PMID: 34861158 Free PMC article. No abstract available.