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. 2022 Oct 1;44(7):351-353.
doi: 10.1097/MPH.0000000000002431. Epub 2022 Feb 18.

Introduction of Hydroxyurea Therapy to a Cohort of Sickle Cell Patients in Northern Haiti

Michele Paul-Hanna  1 , Wesline Joseph  1 , Woodgina Mondesir  1 , Edward V S Faustino  2 , Michael F Canarie  2
Affiliations

Introduction of Hydroxyurea Therapy to a Cohort of Sickle Cell Patients in Northern Haiti

Michele Paul-Hanna et al. J Pediatr Hematol Oncol. .

Abstract

Although the prevalence of sickle cell anemia is high in Haiti, treatment with hydroxyurea (HU) is uncommon. HU therapy was started at a hospital in Northern Haiti for children and young adults who had presented with complications of their disease. The patients were followed in clinic for their response to therapy and the principal outcome was hospitalization for complications. There was a 70% decrease in the rate of hospitalization in the cohort with no significant complications or deaths during the study period. Treatment with HU is a proven therapy that reduces the morbidity associated with sickle cell anemia and efforts should be made to assure access and affordability in regions with a high prevalence.

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Conflict of interest statement

The authors declare no conflict of interest.

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