Resistance to fascioliasis--a review

Abstract

Attempts to actively stimulate or passively transfer resistance to Fasciola hepatica or F. gigantica in various laboratory and farm animals including mice, rats, rabbits, sheep, goats and cattle have been reviewed. These attempts comprised sensitization by primary homologous or heterologous normal or irradiated infections per os, sensitization by subcutaneous, intramuscular or intraperitoneal implantation with the various fluke stages, sensitization by somatic extracts or metabolic products of mature or immature flukes and passive transfer of resistance by immune serum or sensitized lymphocytes.