Review

. 2022 Oct;18(10):1957-1968.

doi: 10.1002/alz.12588. Epub 2022 Feb 20.

Alzheimer's disease research progress in the Mediterranean region: The Alzheimer's Association International Conference Satellite Symposium

Claire Sexton¹, Michele Solis², Judith Aharon-Peretz³, Panagiotis Alexopoulos⁴, Liana G Apostolova⁵, Eléonore Bayen^{6

7}, Betty Birkenhager⁸, Stefano Cappa^{9

10}, Fofi Constantinidou¹¹, Juan Fortea¹², Debby L Gerritsen¹³, Hany I Hassanin^{7

14}, Agustin Ibanez^{7

15

16

17}, Panagiotis Ioannidis¹⁸, Elissaios Karageorgiou¹⁹, Amos Korczyn²⁰, Iracema Leroi²¹, Bjorn Lichtwarck²², Giancarlo Logroscino^{23

24}, Chris Lynch²⁵, Patrizia Mecocci²⁶, Jose Luis Molinuevo^{27

28}, John Papatriantafyllou^{29

30

31}, Sokratis Papegeorgiou^{30

32}, Antonis Politis³³, Rema Raman³⁴, Karen Ritchie³⁵, Pascual Sanchez-Juan³⁶, Mary Sano³⁷, Nikolas Scarmeas^{32

38}, Luiza Spiru^{39

31}, Afroditi Stathi⁴⁰, Magda Tsolaki⁴¹, Görsev Yener⁴², Ioannis Zaganas⁴³, Stelios Zygouris⁴⁴, Maria Carrillo¹

Affiliations

¹ Alzheimer's Association, 225 N Michigan Avenue, 17th Fl, Chicago, Illinois, USA.
² Freelance science writer, Seattle, Washington, USA.
³ Rambam Health Care Campus, Rappapaort School of Medicine, Haifa, Israel.
⁴ Department of Psychiatry, Patras University Hospital, Faculty of Medicine, School of Health Sciences, University of Patras, Patras, Greece.
⁵ Indiana University, Bloomington, IN, USA.
⁶ Laboratoire d'imagerie biomédicale, Sorbonne Université, department of physical rehabilitation medicine, Pitié-Salpêtrière hospital, AP-HP, Paris, France.
⁷ Global Brain Health Institute, University of California San Francisco, San Francisco, California, USA.
⁸ Department of General Practice and Elderly Care Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
⁹ University School for Advanced Studies (IUSS-Pavia) and IRCCS Mondino Foundation, Pavia, Italy.
¹⁰ IRCCS Mondino Foundation, Pavia, PV, Italy.
¹¹ Department of Psychology & Center for Applied Neuroscience, University of Cyprus, Nicosia, Cyprus.
¹² Sant Pau Memory Unit, Neurology Department, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau- Universitat Autònoma de Barcelona, Barcelona, Spain.
¹³ Radboud Medical Center Nijmegen, Nijmegen, the Netherlands.
¹⁴ Geriatric Medicine Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
¹⁵ Trinity College Dublin, Dublin, Ireland.
¹⁶ Latin American Institute for Brain Health (BrainLat), Universidad Adolfo Ibanez, Santiago, Chile.
¹⁷ Universidad de San Andres & National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina.
¹⁸ Aristotle University of Thessaloniki, Thessaloniki, Greece.
¹⁹ Neurological Institute of Athens, Athens, Greece.
²⁰ Tel Aviv University, Tel Aviv, Israel.
²¹ Trinity College Dublin, Global Brain Health Institute, Dublin, Ireland.
²² The Centre for Age-related Functional Decline and Disease, Innlandet Hospital Trust, Ottestad, Norway.
²³ Center for Neurodegenerative Diseases and the Aging Brain Department of Clinical Research in Neurology of the University of Bari at "Pia Fondazione Card G. Panico" Hospital Tricase (Le), Bari, Italy.
²⁴ Department of Basic Medicine Neuroscience and Sense Organs University Aldo Moro Bari, Bari, Italy.
²⁵ Alzheimer's Disease International, London, UK.
²⁶ Institute of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
²⁷ H Lundbeck A/S.
²⁸ BarcelonaBeta Brain Research Center, Barcelona, Spain.
²⁹ Third Age Center IASIS, Athens-Glyfada, Athens, Greece.
³⁰ 1st University Neurology Department, Eginitio Hospital, Athens, Greece.
³¹ Ana Aslan International Foundation.
³² National and Kapodistrian University of Athens, Athens, Greece.
³³ 1st Department of Psychiatry, National and Kapodistrian University of Athens, Athens, Greece.
³⁴ Alzheimer's Therapeutic Research Institute, University of Southern California, CA, USA.
³⁵ INSERM, France.
³⁶ Institute for Research Marqués de Valdecilla (IDIVAL), CIBERNED, University of Cantabria and Department of Neurology, Marqués de Valdecilla University Hospital, Santander, Spain.
³⁷ The Mount Sinai Hospital, New York, NY, USA.
³⁸ Columbia University, New York, NY, USA.
³⁹ Carol Davila University of Medicine and Pharmacy Bucharest, Bucharest, Romania.
⁴⁰ School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK.
⁴¹ 1st Department of Neurology, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Makedonia, Greece.
⁴² Faculty of Medicine, Izmir University of Economics, Izmir, Turkey.
⁴³ Neurogenetics Laboratory, Medical School, University of Crete.
⁴⁴ Centre for Research and Technology Hellas/ Information Technologies Institute, Thessaloniki, Greece.

PMID: 35184367
PMCID: PMC11066754
DOI: 10.1002/alz.12588

Review

Alzheimer's disease research progress in the Mediterranean region: The Alzheimer's Association International Conference Satellite Symposium

Claire Sexton et al. Alzheimers Dement. 2022 Oct.

. 2022 Oct;18(10):1957-1968.

doi: 10.1002/alz.12588. Epub 2022 Feb 20.

Authors

Affiliations

¹ Alzheimer's Association, 225 N Michigan Avenue, 17th Fl, Chicago, Illinois, USA.
² Freelance science writer, Seattle, Washington, USA.
³ Rambam Health Care Campus, Rappapaort School of Medicine, Haifa, Israel.
⁴ Department of Psychiatry, Patras University Hospital, Faculty of Medicine, School of Health Sciences, University of Patras, Patras, Greece.
⁵ Indiana University, Bloomington, IN, USA.
⁶ Laboratoire d'imagerie biomédicale, Sorbonne Université, department of physical rehabilitation medicine, Pitié-Salpêtrière hospital, AP-HP, Paris, France.
⁷ Global Brain Health Institute, University of California San Francisco, San Francisco, California, USA.
⁸ Department of General Practice and Elderly Care Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
⁹ University School for Advanced Studies (IUSS-Pavia) and IRCCS Mondino Foundation, Pavia, Italy.
¹⁰ IRCCS Mondino Foundation, Pavia, PV, Italy.
¹¹ Department of Psychology & Center for Applied Neuroscience, University of Cyprus, Nicosia, Cyprus.
¹² Sant Pau Memory Unit, Neurology Department, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau- Universitat Autònoma de Barcelona, Barcelona, Spain.
¹³ Radboud Medical Center Nijmegen, Nijmegen, the Netherlands.
¹⁴ Geriatric Medicine Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
¹⁵ Trinity College Dublin, Dublin, Ireland.
¹⁶ Latin American Institute for Brain Health (BrainLat), Universidad Adolfo Ibanez, Santiago, Chile.
¹⁷ Universidad de San Andres & National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina.
¹⁸ Aristotle University of Thessaloniki, Thessaloniki, Greece.
¹⁹ Neurological Institute of Athens, Athens, Greece.
²⁰ Tel Aviv University, Tel Aviv, Israel.
²¹ Trinity College Dublin, Global Brain Health Institute, Dublin, Ireland.
²² The Centre for Age-related Functional Decline and Disease, Innlandet Hospital Trust, Ottestad, Norway.
²³ Center for Neurodegenerative Diseases and the Aging Brain Department of Clinical Research in Neurology of the University of Bari at "Pia Fondazione Card G. Panico" Hospital Tricase (Le), Bari, Italy.
²⁴ Department of Basic Medicine Neuroscience and Sense Organs University Aldo Moro Bari, Bari, Italy.
²⁵ Alzheimer's Disease International, London, UK.
²⁶ Institute of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
²⁷ H Lundbeck A/S.
²⁸ BarcelonaBeta Brain Research Center, Barcelona, Spain.
²⁹ Third Age Center IASIS, Athens-Glyfada, Athens, Greece.
³⁰ 1st University Neurology Department, Eginitio Hospital, Athens, Greece.
³¹ Ana Aslan International Foundation.
³² National and Kapodistrian University of Athens, Athens, Greece.
³³ 1st Department of Psychiatry, National and Kapodistrian University of Athens, Athens, Greece.
³⁴ Alzheimer's Therapeutic Research Institute, University of Southern California, CA, USA.
³⁵ INSERM, France.
³⁶ Institute for Research Marqués de Valdecilla (IDIVAL), CIBERNED, University of Cantabria and Department of Neurology, Marqués de Valdecilla University Hospital, Santander, Spain.
³⁷ The Mount Sinai Hospital, New York, NY, USA.
³⁸ Columbia University, New York, NY, USA.
³⁹ Carol Davila University of Medicine and Pharmacy Bucharest, Bucharest, Romania.
⁴⁰ School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK.
⁴¹ 1st Department of Neurology, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Makedonia, Greece.
⁴² Faculty of Medicine, Izmir University of Economics, Izmir, Turkey.
⁴³ Neurogenetics Laboratory, Medical School, University of Crete.
⁴⁴ Centre for Research and Technology Hellas/ Information Technologies Institute, Thessaloniki, Greece.

PMID: 35184367
PMCID: PMC11066754
DOI: 10.1002/alz.12588

Abstract

As research and services in the Mediterranean region continue to increase, so do opportunities for global collaboration. To support such collaborations, the Alzheimer's Association was due to hold its seventh Alzheimer's Association International Conference Satellite Symposium in Athens, Greece in 2021. Due to the COVID-19 pandemic, the meeting was held virtually, which enabled attendees from around the world to hear about research efforts in Greece and the surrounding Mediterranean countries. Research updates spanned understanding the biology of, treatments for, and care of people with Alzheimer's disease (AD_ and other dementias. Researchers in the Mediterranean region have outlined the local epidemiology of AD and dementia, and have identified regional populations that may expedite genetic studies. Development of biomarkers is expected to aid early and accurate diagnosis. Numerous efforts have been made to develop culturally specific interventions to both reduce risk of dementia, and to improve quality of life for people living with dementia.

Keywords: Alzheimer's disease; biomarkers; care; dementia; genetics; prevention.

PubMed Disclaimer

Conflict of interest statement

Claire Sexton is a full-time employee of the Alzheimer’s Association and, in the past 36 months, reports consultation fees from Jazz Pharmaceuticals and support for attending meetings and / or travel to the AAIC Satellite Symposium Sydney (2019) and Society for the Study of Ingestive Behavior (SSIB) Annual Meeting (2019). CES reports an unpaid role as a trustee of Dementia Adventure (2018-2020).

Michelle Solis is a freelance science writer and, in the past 36 months, reports contracts from Lieber Institute for Brain Development, Simons Foundation Autism Research Initiative, Scientific American, American Chemical Society, Pharmaceutical Journal ,Allen Institute for Brain Science; payment or honoraria for articles or reports written for Lieber Institute for Brain Development, Simons Foundation Autism Research Initiative, Scientific American, American Chemical Society, Pharmaceutical Journal, Allen Institute for Brain Science.

Judith Aharon-Peretz in the past 36 months reports consultation fees from Medison.

Panagiotis Alexopoulos in the past 36 months reports payment or honoraria and support for attending meetings and / or travel from Vianex Pharmaceutical company.

Liana Apostolova in the past 36 months, reports grants or contracts from NIH, Alzheimer Association, AVID Pharmaceuticals, Life Molecular Imaging, Roche Diagnostics; received consulting fees from Biogen, Two Labs, IQVIA, NIH, Florida Dept. Health, NIH Biobank, Eli Lilly; received payment or honoraria from AAN, MillerMed, ASiM, Health and Hospitality; Corporation, Mayo Clinic; received support for attending meetings and / or travel from Alzheimer’s Association; participated on a DSMB or Advisory Board for IQVIA, NIA R01 AG061111, UAB Nathan Schock Center; held stock or stock options in Semiring Inc., Cassava Inc; received equipment, materials, drugs, medical writing, gifts, or other services from AVID Pharmaceuticals, Life Molecular Imaging, Roche Diagnostics.

Eléonore Bayen in the past 36 months reports grants or contracts from Covid Solidarity Grant, Atlantic Institute; reports participation on the Advisory Board of SafelyYou company (https://www.safely-you.com/).

Betty Birkenhager has nothing to disclose.

Stefanno Cappa in the past 36 months reports grants or contracts from the Italian Ministry of Health (Ricerca Corrente, Neuroscience and Neurorehabilitation Network); received speaker fees from Biogen, Roche, Nutricia.

Fofi Constantinidou is a salaried employee, University of Cyprus and, in the past 36 months reports grants or contracts from Constantinidou, F. (PI). ACESO: Treatment of Awareness Deficits in Acquired Brain Injuries to Improve Patient Outcomes. Agency: Cyprus Research Innovation Foundation. Grant Period: 2 years, 2020-2022. Excellence/1218/0117; Constantinidou, F. (PI). The Brain Injury Neurorehabilitation Project (Duration: 3 years). Agency: Cyprus Research Innovation Foundation, Grant Period: 3 years, 2019-2022. Excellence/1216/0411; Constantinidou, F. (PI). The Neurocognitive Study for the Aging-Expanded. (Duration: 3 years). Agency: Cyprus Research Innovation Foundation. Grant Period: 3 years, 2019-2022. Excellence/1216/0404.; Koushiou, M (PI).. Constantinidou, F (Partner). It’s a matter of the heart: Developmental and Emotional Adjustment Risks in young children with Congenital Heart Disease. Post-Doc/0916/0257 Agency: Cyprus Research Innovation Foundation. Funded for 30 months: 2019-2022; Leroy, I (U Manchester, PI)……F Constantinidou (Partner). Ears, Eyes and Mind: The “SENSE-Cog Project” to promote mental well-being in elderly Europeans. 1/16 (Duration: 5 years). Agency: EU, H2020-PHC-2015 (#668648). Reports payment or honoraria from Iberoamerican Congress, Invited Presentation (2021); Korean Rehabilitation Research Symposium (2021), participated on a DSMB or Advisory Board for the Sense-Cog project. Held a leadership or fiduciary role for ACRM, ESLA, Cyprus Association of Registered SLPs.

Juan Fortea in the past 36 months reports grants or contracts from Fondo de Investigaciones Sanitario (FIS), Instituto de Salud Carlos III (grants PI14/01126 and PI17/01019); National Institutes of Health (NIA grants 1R01AG056850 - 01A1; R21AG056974 and R01AG061566); Fundació La Marató de TV3 (grant 20141210); Generalitat de Catalunya (grant SLT006/17/00119); Fundació Catalana Síndrome de Down and Fundació Víctor Grífols i Lucas partially supported this work, all paid to his institution. He served as a consultant for Novartis and Lundbeck. Received honoraria for lectures from Roche, NovoNordisk, Esteve and Biogen; payments were made to him. Dr Fortea has a patent WO2019175379 A1 Markers of synaptopathy in neurodegenerative disease issued; he served on advisory boards for AC Immune, Zambon and Lundbeck. He held a leadership or fiduciary role for Spanish Neurological Society, T21 Research Society, Lumind foundation, Jérôme-Lejeune Foundation, Alzheimer’s Association with no payments, and from National Institutes of Health, with payments for the participation in Study Sections. He reports his institution received support from AC Immune to acquire Quanterix NfL Kits.

Debby L. Gerritsen in the past 36 months reports grants or contracts from The Netherlands Organization for Health Research and Development and the Dutch Alzheimer Society; received payment or honoraria for training a group of geropsychologists about depression in long term care; received support for attending meetings and/or travel for presenting at the Krems Dementia Conference in 2019 and the Alzheimer Europe Conference in 2019; held a leadership or fiduciary role for Dutch committee on acknowledging quality of interventions in long term care.

Hany I. Hassanin in the past 36 months reports travel support from the Atlantic Institute to attend the Atlantic senior Fellow ceremony in Oxford, UK, July 2019.

Agustin Ibanez in the past 36 months reports partial support by grants from CONICET; ANID/FONDECYT Regular (1210176, 1210195); FONCYT-PICT 2017-1820; ANID/FONDAP/15150012; Takeda CW2680521; Sistema General de Regalías (BPIN2018000100059), Universidad del Valle (CI 5316); Alzheimer’s Association GBHI ALZ UK-20-639295; and the MULTI-PARTNER CONSORTIUM TO EXPAND DEMENTIA RESEARCH IN LATIN AMERICA [ReDLat, supported by National Institutes of Health, National Institutes of Aging (R01 AG057234), Alzheimer’s Association (SG-20-725707), Rainwater Charitable foundation - Tau Consortium, and Global Brain Health Institute)]. The contents of this publication are solely the responsibility of the authors and do not represent the official views of these Institutions. He received travel support; Alzheimer’s Association GBHI ALZ UK-20-639295. He held the role as President for the Latin American Chapter of the Society for Social Neuroscience.

Panagiotis Ioannidis has nothing to disclose.

Elissaios Karageorgiou in the past 36 months reports EU Horizon2020 grant; received consulting fees for unrelated clinical trials safety board; received payment or honoraria for lectures; received support for attending meetings and/or travel via active grants; hold stock in the Neurological Institute of Athens; have you received equipment, materials, drugs, medical writing, gifts, or other services as part of planned grant budget.

Amos Korczyn in the past 36 months held a volunteer role as Chairperson of the MSAP of the Israeli Alzheimer Association, EMDA.

Iracema Leroi in the past 36 months reports grants or contracts from European Union, Horizon 2020 grantHealth Research Board, Ireland x2, Trinity College Dublin Covid Response Grant, Irish Research Board and ESTHER Ireland; received consulting fees for advisory board from Biogen x 1; participated on DSMB for NIHR funded trial in the UK; held a role as Director, Lewy Body Ireland.

Bjorn Lichtwarck has nothing to disclose.

Giancarlo Logroscino in the past 36 months received payment or honoraria from Roche, GE-General Electric, Amplifon.

Chris Lynch has nothing to disclose.

Patrizia Mecocci in the past 36 months received payment or honoraria from Roche, Neopharmed-Gentili, Neuraxpharm.

Jose Luis Molinuevo in the past 36 months reports the project leading to these results has received funding from “la Caixa” Foundation (ID 100010434), under agreement LCF/PR/GN17/50300004 and the Alzheimer’s Association and an international anonymous charity foundation through the TriBEKa Imaging Platform project (TriBEKa-17-519007). Additional support has been received from the Universities and Research Secretariat, Ministry of Business and Knowledge of the Catalan Government under the grant no. 2017-SGR-892; received consulting fees as consultant or at advisory boards for the following for-profit companies: Roche Diagnostics, Genentech, Novartis, Lundbeck, Oryzon, Biogen, Lilly, Janssen, Green Valley, MSD, Eisai, Alector, BioCross, GE Healthcare, ProMIS Neurosciences, NovoNordisk, Zambón, Cytox and Nutricia; received payment or honoraria by the following for-profit companies: Roche Diagnostics, Lundbeck, Biogen, Eisai, Zambón, and Nutricia; reports as consultant or at advisory boards for the following for-profit companies, or has given lectures in symposia sponsored by the following for-profit companies: Roche Diagnostics, Genentech, Novartis, Lundbeck, Oryzon, Biogen, Lilly, Green Valley, MSD, Eisai, Alector, ProMIS Neurosciences, NovoNordisk, Cytox.

John Papatriantafyllou in the past 36 months received honoraria for lecture from Lavipharm Hellas; held president role for Hellenic Dementia Society - unpaid.

Sokratis Papegeorgiou has nothing to disclose.

Antonis Politis has nothing to disclose.

Rema Raman in the past 36 months received research funding from the National Institute on Aging (NIA), Alzheimer’s Association, Eli Lilly, Janssen and Eisai. She serves as the Vice-Chair of the Board for the Alzheimer’s Association’s San Diego/Imperial Chapter.

Karen Ritchie has nothing to disclose.

Pascual Sanchez-Juan in the past 36 months reports support by grants from IDIVAL, Instituto de Salud Carlos III (Fondo de Investigación Sanitario, PI08/0139, PI12/02288, PI16/01652), JPND (DEMTEST PI11/03028), the CIBERNED program, Siemens Healthineers (Valdecilla Study of Memory and Brain Aging); reports consulting for Roche, Zambon, and Biocross; received payment from Roche and Nutricia for educational events; participated in advisory boards for Roche, Zambon and Biocross.

Mary Sano in the past 36 months reports grants or contracts from NIA and consulting fees from Avenir, Biogen Idec, BioXcel, Eisai, Genentech, F. Hoffman LaRoche, Minerva Neuroscience, Novartis, NovoNordisk, Pfizer, vTv Therapeutics, Karuna. MS has received support for attending meetings and/or travel for Alzheimer’s Association activities as a member of the Medical and Scientific Advisory Group (MSAG). MS has participated in a Data Safety Monitoring Board or Advisory Board for Syneos and reports roles as President of the International Psychogeriatric Association and Board Member of the National Association of Veteran Research and Education Foundations.

Nikolas Scarmeas in the past 36 months received grants or contracts from EISAI Elenbecestat clinical tiral - Recruiting site for multinational, multicenter industry sponsored phase III treatment trial for Alzheimer’s disease; EPAD study - Recruiting site for multinational, multicenter IMI sponsored observational study of prodromal stages of dementia - both paid to his institution; received honorarium for delivering 3 scientific presentations in Korea - Aricept International Symposium; served as Chair of Data Safety Monitoring Board for Albert Einstein College of Medicine - NIH funded clinical trial.

Luiza Spiru in the past 36 months reports grants or contracts from European Commission, Pharma Industry, Private Sector, National Ministry of Research and Education; received payment as Independent Expert on Ethics, Innovation and Gerontechnology Aging- Noncommunicable Diseases, for the EU Commission; received support for attending meetings and/or travel from the EU Commission, Private funds; have patent pending - original formula for Nutritional Supplements; participated on a Data Safety Monitoring Board or Advisory Board for EU Projects: 2019 - 2023: Principal Investigator and coordinator for in the european research project RADAR-AD (Remote Assessment of Disease and Relapse - Alzheimer’s Disease) within IMI 2 (Innovative Medicine Initiative), Grant Nr. 806999, financed from H2020 R&D and EFPIAprograms; 2018- 2021: PETAL project: AAL-2016 [Ambient Assistive Living: intelligent lights to be used for the cognitive delay MCI patients, independent seniors, at home or in residential houses, out/in patients for Memory Clinics]; 2018-2022: IOANNA project: AAL-2017 [Integration Of All stores Network and Navigation Assistant]; 2018- 2022: Ella4Life project: AAL-2017 [Virtual Assistant for Seniors]; 2019: VirtuAAL project: AAL-2018 SCP [Virtual And Augmented Reality For Combating Cognitive Impairment]; 2019- 2022: FrAAgiLe project: AAL-2018 [Platform for detecting frailty and falls]; 2019-2021: POSITIVE project: AAL-2018 [Personalized Platform assisting seniors in healthy fulfilled and active life]; 2019-2023: SMART BEAR EC H2020 Project [Smart Big Data Platform to Offer Evidence-based Personalized Support for Healthy and Independent Living at Home] - coordonating the Romanian Pilot of 1,000 elderlies at home; 2020-2022: iCan project: AAL-2019 [ICT-based assistant for everyday life]; 2020-2023: ReMember-Me project: AAL-2019 [Smart assistant to prevent and detect cognitive decline, promote cognitive function and social inclusion among older adults]. Held role: UNPAID, 2020-2024: COST Action CA 19121 (GoodBrother: Network on Privacy - Aware Audio- and Video-Based Applications for Active and assisted living) member of the Management Committee for Romania and leader of WG 3 - Audio-and video-based AAL applications; 2020-2024: COST Action CA 19136 (NET4AGE-FRIENDLY: International Interdisciplinary Network on Smart Healthy Age-friendly Environments) member of the Management Committee for Romania and leader of WG 4 - SHAFE impact and sustainability: policy development, funding forecast, and cost-benefit evaluations.

Afroditi Stathi in the past 36 months reports grants or contracts from National Institute for Health Research - Public Health Research Programme (UK). A multi-centre randomised controlled trial of a peer-volunteer led active ageing programme to prevent decline in physical function in older people at risk of mobility disability. The ACE (Active, Connected, Engaged) study. 2021-2025; received travel funding to visit and collaborate with colleagues at the University of Sydney, Australia. Participate as Trial Steering Committee Member: NIHR-Health Technology Assessment Programme. Home Health Promotion Intervention for people with mild frailty. University College London. (2020-2023); Chair of Scientific Advisory Committee for the study: “Understanding the experiences of physically inactive people in mid-life” study. Led by the University of Bristol and funded by the Centre for Ageing Better (2020-2021); Invited Advisory Committee Member. European Research Council study: “Meaningful Mobility: A novel approach to movement within and between places in later life”. University of Groningen, Netherlands, 2-3 September.

Magda Tsolaki has nothing to disclose.

Görsev Yener in the past 36 months reports a Project Grant from TÜBİTAK (National Funding Agency), that stands for The Scientific and Technological Research Council of Turkey.

Ioannis Zaganas in the past 36 months received support for attending meetings and/or travel from Akcea, Biomarin, Sanofi Genzyme; participated on a DSMB or Advisory Board for BioMarin, Genesis Pharma, Sanofi Genzyme.

Stelios Zygouris in the past 36 months reports grants or contracts from Global Brain Health Institute & Alzheimer’s Association Pilot Awards for Global Brain Health Leaders (Grant funding for project GBHI_ALZ-18-541600, “A two-tiered cost-efficient computerized cognitive screening protocol.”); received support from Global Brain Health Institute funding for attending the Alzheimer’s Association International Conference (AAIC) Satellite Symposium, Sao Paulo, Brazil (April 10-12, 2019).

M Carrillo is a full-time employee of the Alzheimer’s Association and reports, in the past 36 months, participating on a Data Safety Monitoring Board or Advisory Board for US POINTER and holding a role for EASTERSEALS.

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Alzheimer's disease research progress in the Mediterranean region: The Alzheimer's Association International Conference Satellite Symposium

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Alzheimer's disease research progress in the Mediterranean region: The Alzheimer's Association International Conference Satellite Symposium

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