Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jan;15(1):58-64.
doi: 10.25122/jml-2019-0142.

Functional tests in patients with ischemic heart disease

Affiliations

Functional tests in patients with ischemic heart disease

Rodica Lucia Avram et al. J Med Life. 2022 Jan.

Abstract

Lately, easier and shorter tests have been used in the functional evaluation of cardiac patients. Among these, walking speed (WS) and Timed Up and Go (TUG) tests are associated with all-cause mortality, mainly cardiovascular and the rate of re-hospitalization, especially in the elderly population. We prospectively analyzed a group of 38 patients admitted to the Cardiology Clinic from Elias Hospital, Romania, with chronic coronary syndrome (CCS) (n=22) and STEMI (n=16). We assessed the patients immediately after admission and before discharge with G-WALK between the 1st and 30th of September 2019. Our study group had a mean age of 62.7±12.1 years. Patients with a low WS were older (69.90±12.84 vs. 59.90±10.32 years, p=0.02) and had a lower serum hemoglobin (12.38±1.20 vs. 13.72±2.07 g/dl, p=0.02). The WS significantly improved during hospitalization (p=0.03) after optimal treatment. The TUG test performed at the time of admission had a longer duration in patients with heart failure (14.05 vs. 10.80 sec, p=0.02) and was influenced by patients' age (r=0.567, p=0.02), serum creatinine (r=0.409, p=0.03) and dilation of right heart chambers (r=0.399, p=0.03). WS and TUG tests can be used in patients with CCS and STEMI, and are mainly influenced by age, thus having a greater value among the elderly.

Keywords: 6MWT – 6-minute walk test; CCS – chronic coronary syndrome; CKD – chronic kidney disease; COPD – chronic obstructive pulmonary disease; CPET – cardiopulmonary exercise testing; HF – heart failure; IHD – ischemic heart disease; IMT – intima-media thickness; MDRD – Modification of Diet in Renal Disease; STEMI – ST elevation myocardial infarction; TUG – Timed Up and Go; Timed Up and Go test; WS – walking speed; functional capacity; functional walk tests; ischemic heart disease; walking speed.

PubMed Disclaimer

References

    1. Townsend N, Wilson L, Bhatnagar P, Wickramasinghe K, et al. Cardiovascular disease in Europe: epidemiological update 2016. Eur Heart J. 2016 Nov 7;37(42):3232–45. doi: 10.1093/eurheartj/ehw334. - DOI - PubMed
    1. Newman AB, Gottdiener JS, McBurnie MA, Hirsch CH, et al. Associations of subclinical cardiovascular disease with frailty. Journals Gerontol - Ser A Biol Sci Med Sci. 2001;56(3):M158–66. doi: 10.1093/gerona/56.3.m158. - DOI - PubMed
    1. Vermeulen J, Neyens JC, Van Rossum E, Spreeuwenberg MD, De Witte LP. Predicting ADL disability in community-dwelling elderly people using physical frailty indicators: A systematic review. BMC Geriatr. 2011:11. doi: 10.1186/1471-2318-11-33. - DOI - PMC - PubMed
    1. Rostagno C, Olivo G, Comeglio M, Boddi V, et al. Prognostic value of 6-minute walk corridor test in patients with mild to moderate heart failure: comparison with other methods of functional evaluation. Eur J Heart Fail. 2003 Jun;5(3):247–52. doi: 10.1016/s1388-9842(02)00244-1. - DOI - PubMed
    1. Bittner V, Weiner DH, Yusuf S, Rogers WJ, et al. Prediction of mortality and morbidity with a 6-minute walk test in patients with left ventricular dysfunction. SOLVD Investigators. JAMA. 1993 Oct 13;270(14):1702–7. - PubMed