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. 2022 Feb;52(2):318-321.
doi: 10.1111/imj.15687.

Hospitalisation and associated costs of gastrointestinal bleeding from primary prevention aspirin use in South Australia: a retrospective case series analysis

Gregory Roberts  1   2 , Maxwell Baker  2 , Hannah Leiblich  2 , Maryssa Paulose  2 , Matthew Pegoli  1 , Lucas Panagopoulos  3 , Carly Schiller  4 , Vijayaprakash Suppiah  2
Affiliations

Hospitalisation and associated costs of gastrointestinal bleeding from primary prevention aspirin use in South Australia: a retrospective case series analysis

Gregory Roberts et al. Intern Med J. 2022 Feb.

Abstract

We assessed hospitalisations for gastrointestinal bleeding directly related to primary prevention aspirin in lower risk patients for a 6-month period in three South Australian hospitals. Those with related underlying pathology or concurrent causative medication were excluded. Identified patients (n = 22) carried little co-morbidity, 41% received prior proton-pump inhibitors and 68% were aged >70 years. Mean hospital admission cost was $6769 (95% confidence interval $5198-$8340), with projected state and national annual costs of $0.57 and $8.12 million respectively. In light of recent guideline changes, clinicians need to vigorously assess the need for primary prevention aspirin.

Keywords: adverse drug reaction; aspirin; cost; deprescribing; gastrointestinal bleeding; primary prevention.

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References

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