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. 1986;49(4):219-23.
doi: 10.1159/000242534.

Adrenal phenylethanolamine-N-methyltransferase activity in the young rat: influence of thyroid hormones and insulin-induced hypoglycemia

D Gripois, M Valens

Adrenal phenylethanolamine-N-methyltransferase activity in the young rat: influence of thyroid hormones and insulin-induced hypoglycemia

D Gripois et al. Biol Neonate. 1986.

Abstract

The postnatal evolution of adrenal phenylethanolamine-N-methyltransferase (PNMT) activity is slightly accelerated by hypothyroidism and slowed by hyperthyroidism. In 14-day-old rats a single stimulation of the adrenals by insulin-induced hypoglycemia does not lead to any change in enzymatic activity. If the stimulation is repeated for 4 days, it leads to a net increase in adrenal PNMT activity in the control rats, while no increase occurs in hypo- or hyperthyroid animals.

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