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Case Reports
. 2022 Feb 21;37(7):e52.
doi: 10.3346/jkms.2022.37.e52.

Case Reports of Acute Transverse Myelitis Associated With mRNA Vaccine for COVID-19

Hyunjong Eom  1 , Seung Woo Kim  2 , Minkyoung Kim  1 , Ye Eun Kim  1 , Ji Hyun Kim  1 , Ha Young Shin  2 , Hye Lim Lee  3
Affiliations
Case Reports

Case Reports of Acute Transverse Myelitis Associated With mRNA Vaccine for COVID-19

Hyunjong Eom et al. J Korean Med Sci. .

Abstract

Acute transverse myelitis (ATM) has been reported as rare complication of vaccination. Herein, we report 2 cases of ATM after the administration of an mRNA vaccine for coronavirus disease 2019 (COVID-19). The first one is an 81-year-old man who received the BNT162b2 vaccine. He presented with bilateral hand weakness. Spine magnetic resonance imaging (MRI) showed high signal intensity from the C1 to C3 vertebrae. The second is a 23-year-old woman who received the BNT162b2 vaccine and experienced tingling in her legs. Spine MRI showed a high signal intensity lesion at the conus medullaris. These patients were treated with intravenous methylprednisolone and their symptoms improved slightly. Careful follow-up is needed to identify adverse events after the administration of mRNA vaccines for COVID-19.

Keywords: CNS Demyelinating Disease; COVID-19 Vaccine; Transverse Myelitis; mRNA Vaccine.

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Conflict of interest statement

The authors have no potential conflicts of interest to disclose.

Figures

Fig. 1
Fig. 1. (A) Spine MRI showing high signal intensity and multifocal nodular enhancement with an ill-defined signal increase on T2-weighted images from the C1 to C3 vertebrae. (B) Spine MRI showing a high signal intensity lesion without contrast enhancement at the anterior portion of the conus medullaris on T2-weighted images.
MRI = magnetic resonance imaging.
See this image and copyright information in PMC

Comment in

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