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Comment
. 2022 Mar 1;50(3):e323-e324.
doi: 10.1097/CCM.0000000000005405.

The authors reply

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Comment

The authors reply

Matthew S Duprey et al. Crit Care Med. .
No abstract available

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Conflict of interest statement

Dr. van den Boogaard’s institution received funding and support for article research from ZonMw. The remaining authors have disclosed that they do not have any potential conflicts of interest.

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References

    1. Yoshihiro S, Taito S: Concerns With Association Between Incident Delirium Treatment With Haloperidol and Mortality in Critically Ill Adults. Crit Care Med. 2022; 50:e322–e323
    1. Duprey MS, Devlin JW, van der Hoeven JG, et al.: Association between incident delirium treatment with haloperidol and mortality in critically ill adults. Crit Care Med. 2021; 49:1303–1311
    1. van den Boogaard M, Slooter AJC, Brüggemann RJM, et al.; REDUCE Study Investigators: Effect of haloperidol on survival among critically ill adults with a high risk of delirium: The REDUCE randomized clinical trial. JAMA. 2018; 319:680–690
    1. Milbrandt EB, Kersten A, Kong L, et al.: Haloperidol use is associated with lower hospital mortality in mechanically ventilated patients. Crit Care Med. 2005; 33:226–229; discussion 263–265
    1. Rood PJT, van de Schoor F, van Tertholen K, et al.: Differences in 90-day mortality of delirium subtypes in the intensive care unit: A retrospective cohort study. J Crit Care. 2019; 53:120–124

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