Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Meta-Analysis
. 2022 May;84(5):e73-e75.
doi: 10.1016/j.jinf.2022.02.016. Epub 2022 Feb 19.

Meta-analysis of immunologic response after COVID-19 mRNA vaccination in solid organ transplant recipients

Kefu Tang  1 , Xi Wu  2 , Ying Luo  3 , Zhiying Wei  4 , Liyun Feng  3 , Lei Wu  3
Affiliations
Meta-Analysis

Meta-analysis of immunologic response after COVID-19 mRNA vaccination in solid organ transplant recipients

Kefu Tang et al. J Infect. 2022 May.
No abstract available

Keywords: COVID-19; Immunologic response; Solid organ transplant recipients; mRNA vaccine.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest The authors have no conflict of interest to declare.

Figures

Fig. 1
Fig. 1
Serological response in SOTRs. Boxplots of positive serological response rates (%) in SOTRs and healthy controls after different dose of COVID-19 mRNA vaccination (first dose in SORTRs as reference group) (A), positive serological response rates (%) by organ type after partial COVID-19 vaccination and after complete COVID-19 vaccination (liver transplantation receipts as reference group) (B). Summary ORs for anti-spike IgG seronegativity of immunosuppressive treatment (C). Each point indicates a study cohort where data were available. Pairwise comparisons are based on the non-parametric Mann-Whitney U independent-samples test (**<0.01, ***<0.0001).
Fig 2
Fig. 2
Local and systemic toxicities reported in SOTRs after first dose (A), second (B) and third (C) dose vaccination. Each point indicates a study cohort where data were available.
See this image and copyright information in PMC

References

    1. Belsky J.A., Tullius B.P., Lamb M.G., Sayegh R., Stanek J.R., Auletta J.J. COVID-19 in immunocompromised patients: a systematic review of cancer, hematopoietic cell and solid organ transplant patients. J Infect. Mar 2021;82(3):329–338. - PMC - PubMed
    1. Ducloux D., Bamoulid J., Chabannes M., Colladant M., Munshi A., Roubiou C., Seibel J., Tachikart A., Yannaraki M., Crepin T., Courivaud C. Current vaccine strategies against SARS_CoV-2 only poorly protect kidney transplant recipients. J Infect. 2022 Jan 21 S0163-4453(22)00020-2. - PMC - PubMed
    1. Polack F.P., Thomas S.J., Kitchin N., et al. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. N Engl J Med. 2020;383:2603–2615. - PMC - PubMed
    1. Tsapepas D., Husain S.A., King K.L., Burgos Y., Cohen D.J., Mohan S. Perspectives on COVID-19 vaccination among kidney and pancreas transplant recipients living in New York City. Am J Health Syst Pharm. 2021;78(22):2040–2045. - PMC - PubMed
    1. Tharmaraj D., Dendle C., Polkinghorne K.R., Mulley W.R. Kidney transplant recipients' attitudes toward COVID-19 vaccination and barriers and enablers to vaccine acceptance. Transpl Infect Dis. 2021 Oct 25:e13749. - PMC - PubMed