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. 2022 Feb 22;12(1):3022.
doi: 10.1038/s41598-022-06958-2.

Urban-rural prostate cancer disparities in a regional state of Australia

Georgea R Foley  1 , C Leigh Blizzard  1 , Brian Stokes  1 , Marketa Skala  2 , Frank Redwig  3 , Joanne L Dickinson  1 , Liesel M FitzGerald  4
Affiliations

Urban-rural prostate cancer disparities in a regional state of Australia

Georgea R Foley et al. Sci Rep. .

Abstract

Men living in regional and remote areas experience disparities in prostate cancer (PrCa) diagnosis, clinical characteristics and treatment modalities. We sought to determine whether such disparities exist in PrCa patients from Tasmania; a regional state of Australia with the second-highest rate of diagnosis and where over a third of residents live in outer regional and remote areas. Our study included clinicopathological data from 1526 patients enrolled in the Prostate Cancer Outcomes Registry-Tasmania. Regression analyses were undertaken to determine whether demographic, clinical and treatment variables differed between inner regional and outer regional/remote patients. Men from outer regional/remote areas were significantly more likely to reside in lower socio-economic areas, be diagnosed at a later age and with more clinically aggressive features. However, in contrast to previous studies, there were no overall differences in diagnostic or treatment method, although men from outer regional/remote areas took longer to commence active treatment and travelled further to do so. This study is the first to investigate PrCa disparities in a wholly regional Australian state and highlights the need to develop systematic interventions at the patient and healthcare level to improve outcomes in outer regional and remote populations in Australia and across the globe.

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Conflict of interest statement

The authors declare no competing interests.

References

    1. Stokes B, Albion T, Otahal P, & Venn A. Cancer in Tasmania: Incidence and Mortality 2015. Hobart: Menzies Institute for Medical Research Tasmania; 2017.
    1. Baade PD, Youlden DR, Coory MD, Gardiner RA, Chambers SK. Urban–rural differences in prostate cancer outcomes in Australia: What has changed? Med. J. Aust. 2011;194(6):293–296. doi: 10.5694/j.1326-5377.2011.tb02977.x. - DOI - PubMed
    1. Coory MD, Baade PD. Urban–rural differences in prostate cancer mortality, radical prostatectomy and prostate-specific antigen testing in Australia. Med. J. Aust. 2005;182(3):112–115. doi: 10.5694/j.1326-5377.2005.tb06609.x. - DOI - PubMed
    1. Ruseckaite R, Sampurno F, Millar J, Frydenberg M, Evans S. Diagnostic and treatment factors associated with poor survival from prostate cancer are differentially distributed between regional and metropolitan Victoria, Australia. BMC Urol. 2016;16(1):54. doi: 10.1186/s12894-016-0172-4. - DOI - PMC - PubMed
    1. Ruseckaite R, Beckmann K, O'Callaghan M, Roder D, Moretti K, Millar J, et al. A retrospective analysis of Victorian and South Australian clinical registries for prostate cancer: trends in clinical presentation and management of the disease. BMC Cancer. 2016;16:607. doi: 10.1186/s12885-016-2655-9. - DOI - PMC - PubMed