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. 2022 May;42(4):873-875.
doi: 10.1007/s10875-021-01194-1. Epub 2022 Feb 23.

Peeling Skin Syndrome Type 1: Dupilumab Reduces IgE, But Not Skin Anomalies

Barranca Alexis  1 , Jonca Nathalie  2 , Martin-Blondel Audrey  3 , Apoil Pol-André  4   5 , Mazereeuw-Hautier Juliette  6
Affiliations

Peeling Skin Syndrome Type 1: Dupilumab Reduces IgE, But Not Skin Anomalies

Barranca Alexis et al. J Clin Immunol. 2022 May.

Erratum in

No abstract available

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References

    1. Mazereeuw-Hautier J, Leclerc EA, Simon M, Serre G, Jonca N. A novel mutation in CDSN causes peeling skin disease in a patient from Morocco. Br J Dermatol. 2011;165:1152–5. - DOI
    1. Igawa S, Kishibe M, Honma M, Murakami M, Mizuno Y, Suga Y, et al. Aberrant distribution patterns of corneodesmosomal components of tape-stripped corneocytes in atopic dermatitis and related skin conditions (ichthyosis vulgaris, Netherton syndrome and peeling skin syndrome type B). J Dermatol Sci. 2013;72:54–60. - DOI
    1. Mallet A, Kypriotou M, George K, Leclerc E, Rivero D, Mazereeuw-Hautier J, et al. Identification of the first nonsense CDSN mutation with expression of a truncated protein causing peeling skin syndrome type B. Br J Dermatol. 2013;169:1322–5. - DOI
    1. Li J, Leyva-Castillo JM, Hener P, Eisenmann A, Zaafouri S, Jonca N, et al. Counterregulation between thymic stromal lymphopoietin– and IL-23–driven immune axes shapes skin inflammation in mice with epidermal barrier defects. J Allergy Clin Immunol. 2016;138:150-161.e13. - DOI
    1. Sogkas G, Hirsch S, Jablonka A, Witte T, Schmidt RE, Atschekzei F. Dupilumab to treat severe atopic dermatitis in autosomal dominant hyper-IgE syndrome. Clinical Immunology. 2020;215:108452. - DOI

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