Correction: Bacterial recognition by PGRP-SA and downstream signalling by Toll/DIF sustain commensal gut bacteria in Drosophila

Abstract

[This corrects the article DOI: 10.1371/journal.pgen.1009992.].

Fig 6. Loss of PGRP-SA increases intestinal fat levels.

Loss of PGRP-SA increased intestinal triglyceride levels in 5-day old flies. This phenomenon was suppressed with pharmacological inhibition (rapamycin) or RNAi against TOR in ECs. This was dependent on 4EBP as yw seml; NP1>4E-BP^RNAi treated with rapamycin had fat levels statistically indistinguishable from yw seml. N = 15/genotype/treatment a total of three independent experiments (each with n = 5/genotype/treatment). Values of mutants and controls were statistically compared using student’s t-test (***p<0.001, all other comparisons non-significant except yw seml; NP1>4E-BP^RNAi treated with rapamycin compared to yw, which has a p value<0.001-comparison not shown in the graph).