Particle-labelled immunoassays: a review

Abstract

Up to now, various types of particles have been used as labels in immunoassay. Well known examples are erythrocytes and latex particles. More recently, colloidal gold and dye particles have been introduced as a label. Each type of particle offers one (or more) method(s) of detection which depend(s) on the physical properties of the particles. In this paper, the present state-of-the-art regarding particle-labelled immunoassays will be reviewed.