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. 2022 Dec;11(1):790-792.
doi: 10.1080/22221751.2022.2045878.

Reduced neutralization of SARS-CoV-2 Omicron variant by BNT162b2 vaccinees' sera: a preliminary evaluation

D Mileto  1 , V Micheli  1 , C Fenizia  2   3 , M Cutrera  1 , G Gagliardi  1 , A Mancon  1 , F Bracchitta  1 , A De Silvestri  4 , G Rizzardini  5 , A Lombardi  1 , M Biasin  2 , M R Gismondo  1
Affiliations

Reduced neutralization of SARS-CoV-2 Omicron variant by BNT162b2 vaccinees' sera: a preliminary evaluation

D Mileto et al. Emerg Microbes Infect. 2022 Dec.
No abstract available

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Conflict of interest statement

No potential conflict of interest was reported by the author(s).

Figures

Figure 1.
Figure 1.
SARS-CoV-2 variants of concern (VOC). Panel (A) Neutralization assay (NTA) performed on the SARS-CoV-2 lineage B.1 (EU) and 2 VOCs, d and o. Panels B and C comparison between the Omicron variant and the EU and delta variant, respectively. Lines connect the NTAs of each individual subject. Panel D shows the correlation between anti-SARS-CoV-2 specific antibodies and neutralization assays (NTA) measured 1 month post two doses of the BNT162b2 vaccine. Three weeks after a third dose both antibody titres (Panel E) and neutralizing activity (NA) (Panel F) increased. **** = p <0.0001.
See this image and copyright information in PMC

References

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Supplementary concepts