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. 2022 Feb 11;82(2):181-205.
doi: 10.1055/a-1671-2446. eCollection 2022 Feb.

Diagnosis, Therapy and Follow-up of Cervical Cancer. Guideline of the DGGG, DKG and DKH (S3-Level, AWMF Registry No. 032/033OL, May 2021) - Part 2 with Recommendations on Psycho-oncology, Rehabilitation, Follow-up, Recurrence, Palliative Therapy and Healthcare Facilities

Tanja Fehm  1 , Frederik A Stübs  2 , Martin C Koch  2 , Peter Mallmann  3 , Christian Dannecker  4 , Anna Dietl  2 , Anna Sevnina  2 , Franziska Mergel  2 , Laura Lotz  2 ; Carolin C.Hack; Anne Ehret  1 , Daniel Gantert  1 , Franca Martignoni  1 , Jan-Philipp Cieslik  1 , Jan Menke  5 , Olaf Ortmann  6 , Carmen Stromberger  7 , Karin Oechsle  8 , Beate Hornemann  9 , Friederike Mumm  10 , Christoph Grimm  11 , Alina Sturdza  12 , Edward Wight  13 , Kristina Loessl  14 , Michael Golatta  15 , Volker Hagen  16 , Timm Dauelsberg  17 , Ingo Diel  18 , Karsten Münstedt  19 , Eberhard Merz  20 , Dirk Vordermark  21 , Katja Lindel  22 , Christian Wittekind  23 , Volkmar Küppers  24 , Ralph Lellé  25 , Klaus Neis  26 , Henrik Griesser  27 , Birgit Pöschel  28 , Manfred Steiner  29 , Ulrich Freitag  30 , Tobias Gilster  31 , Alexander Schmittel  32 , Michael Friedrich  33 , Heidemarie Haase  34 , Marion Gebhardt  34 , Ludwig Kiesel  25 , Michael Reinhardt  35 , Michael Kreißl  36 , Marianne Kloke  37 , Lars-Christian Horn  23 , Regina Wiedemann  38 , Simone Marnitz  39 , Anne Letsch  40 , Isabella Zraik  41 , Bernhard Mangold  42 , Jochen Möckel  43 , Céline Alt  44 , Pauline Wimberger  45 , Peter Hillemanns  46 , Kerstin Paradies  47 , Alexander Mustea  48 , Dominik Denschlag  49 , Ulla Henscher  49 , Reina Tholen  50 , Simone Wesselmann  51 , Matthias W Beckmann  2
Affiliations

Diagnosis, Therapy and Follow-up of Cervical Cancer. Guideline of the DGGG, DKG and DKH (S3-Level, AWMF Registry No. 032/033OL, May 2021) - Part 2 with Recommendations on Psycho-oncology, Rehabilitation, Follow-up, Recurrence, Palliative Therapy and Healthcare Facilities

Tanja Fehm et al. Geburtshilfe Frauenheilkd. .

Abstract

Aim This is an update of the interdisciplinary S3-guideline on the Diagnosis, Therapy and Follow-up of Cervical Cancer (AWMF Registry No. 032/033OL), published in March 2021. The work on the updated guideline was funded by German Cancer Aid (Deutsche Krebshilfe) as part of the German Guideline Program in Oncology. The guideline was coordinated by the German Society of Gynecology and Obstetrics ( Deutsche Gesellschaft für Gynäkologie und Geburtshilfe , DGGG) and the Working Group on Gynecological Oncology ( Arbeitsgemeinschaft Gynäkologische Onkologie , AGO) of the German Cancer Society ( Deutsche Krebsgesellschaft , DKG). Method The process used to update the 2014 S3-guideline was based on an appraisal of the available evidence using the criteria of evidence-based medicine, adaptations of existing evidence-based national and international guidelines or - if evidence was lacking - on the consensus of the specialists involved in compiling the update. After an initial review of the current literature was carried out according to a prescribed algorithm, several areas were identified which, in contrast to the predecessor version from September 2014, required new recommendations or statements which would take account of more recently published literature and the recent appraisal of new evidence. Recommendations The short version of this guideline consists of recommendations and statements on palliative therapy and follow-up of patients with cervical cancer. The most important aspects included in this updated guideline are the new FIGO classification published in 2018, the radical open surgery approach used to treat cervical cancer up to FIGO stage IB1, and the use of the sentinel lymph node technique for tumors ≤ 2 cm. Other changes include the use of PET-CT, new options in radiotherapy (e.g., intensity-modulated radiotherapy, image-guided adaptive brachytherapy), and drug therapies to treat recurrence or metastasis.

Keywords: cervical cancer; cervical intraepithelial neoplasia; follow-up; guideline; therapy.

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Conflict of interest statement

Conflict of Interest/Interessenkonflikt The conflicts of interest of all the authors are listed in the long German-language version of the guideline report./Die Interessenkonflikte der Autoren sind im Leitlinienreport aufgelistet.

Figures

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Agreed care algorithm (reviewed in 2021). [rerif]
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Konsentierter Versorgungsalgorithmus (geprüft 2021). [rerif]
See this image and copyright information in PMC

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