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Review
. 2022 Jan 31:75:103308.
doi: 10.1016/j.amsu.2022.103308. eCollection 2022 Mar.

Efficacy of laparoscopic surgery in the treatment of hepatic abscess: A systematic review and meta-analysis

Abdourahmane Ndong  1 , Jacques Noel Tendeng  1 , Adja Coumba Diallo  1 , Alassane Dieye  2 , Mohamed Lamine Diao  1 , Sidy Diallo  3 , Saer Diop  1 , Mamadou Ka Diallo  1 , Moustapha Diedhiou  4 , Mohamed Lamine Fall  4 , Philippe Manyacka Ma Nyemb  1 , Ibrahima Konaté  1
Affiliations
Review

Efficacy of laparoscopic surgery in the treatment of hepatic abscess: A systematic review and meta-analysis

Abdourahmane Ndong et al. Ann Med Surg (Lond). .

Abstract

Background: Liver abscess is a common cause of intra-abdominal infection and its treatment depends on the presentation. Laparoscopy, in addition to its classic benefits, has particular advantages in the management of liver abscess but its role is not well defined and studies done in that field are heterogenous. The objective of this systematic review is to evaluate the efficacy of laparoscopic surgery in the management of liver abscess.

Methods: We realized a systematic review and meta-analysis including studies published in the 20 last years. The primary outcome was the pooled prevalence of recurrent or residual liver abscess after laparoscopic treatment.

Results: We retrieved 190 studies regarding laparoscopic surgery in liver abscess and 17 studies were included in the quantitative and qualitative synthesis. A total of 608 patients was included and 299 of them (49.1%) were treated by laparoscopic surgery. The indications were mainly failure of first line treatment (antibiotic treatment and/or percutaneous drainage and/or needle aspiration) and ruptured multiloculated, or caudate lobe liver abscess. The surgical gesture performed was laparoscopic drainage in all studies. The post-operative rate of recurrent or residual liver abscess after treatment by laparoscopy was 4.22% (95% CI: 2.29-7.07).

Conclusions: This systematic review showed that laparoscopic drainage had a considerable place in the management. The post-operative rate of recurrence was low with no mortality suggesting that laparoscopy is safe and feasible for liver abscess management.

Keywords: Amoebic; Hepatic abscess; Infection; Laparoscopy; Pyogenic; Surgery.

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
PRISMA flow diagram illustrating the search process and study selection.
Fig. 2
Fig. 2
Bias assessment for included studies using ROBINS-I tool.
Fig. 3
Fig. 3
Summary plot of Bias assessment for included studies using ROBINS-I tool.
Fig. 4
Fig. 4
Meta-analysis estimating post-operative rate of recurrent or residual liver abscess after treatment by laparoscopy.
See this image and copyright information in PMC

References

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