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Case Reports
. 2022 Jan 19;14(1):e21420.
doi: 10.7759/cureus.21420. eCollection 2022 Jan.

Mycobacterium marinum Infection and Interferon-Gamma Release Assays Cross-Reactivity: A Case Report

Premalkumar M Patel  1 , Nicholas Camps  1 , Cynthia I Rivera  1 , Claudio Tuda  2 , Garrett VanOstran  1
Affiliations
Case Reports

Mycobacterium marinum Infection and Interferon-Gamma Release Assays Cross-Reactivity: A Case Report

Premalkumar M Patel et al. Cureus. .

Abstract

Mycobacterium marinum (M. marinum) is a pathogen that causes skin and soft tissue infections in people who work with contaminated water, such as fish handlers. M. marinum infection is mostly limited to patients with compromised immune systems. As per current guidelines, susceptibility testing is not routinely recommended, although sporadic cases have been reported with resistance to routinely prescribed anti-tuberculous drugs. We report a case of a 61-year-old male taking adalimumab with ulcerative skin and soft tissue infection with positive interferon-gamma release assays (IGRA) identified as M. marinum and the treatment challenges involved in this case.

Keywords: att resistance; igra cross reactivity; mycobacterium marinum; ntm; ssti.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Pre-treatment ulcerative skin lesion due to Mycobacterium marinum infection
Figure 2
Figure 2. Resolution of skin lesion post susceptibility guided antimicrobial treatment
See this image and copyright information in PMC

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