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Case Reports
. 2022 Jan 19:21:93-96.
doi: 10.1016/j.jdcr.2022.01.006. eCollection 2022 Mar.

A case of systemic lupus erythematosus with cutaneous granulomatous vasculitis

Tina Hsu  1 , Peter Nguyen  2 , Vesna Petronic-Rosic  1
Affiliations
Case Reports

A case of systemic lupus erythematosus with cutaneous granulomatous vasculitis

Tina Hsu et al. JAAD Case Rep. .
No abstract available

Keywords: ANCA, antineutrophil cytoplasmic autoantibodies; EGPA, eosinophilic granulomatosis with polyangiitis; GPA, granulomatosis with polyangiitis; SLE, systemic lupus erythematosus; cutaneous granulomatous vasculitis; discoid lupus; granulomatous vasculitis; lupus vasculitis; systemic lupus erythematosus.

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Conflict of interest statement

None disclosed.

Figures

Fig 1
Fig 1
Scattered, uniform 5- to 10-mm indurated hyperpigmented plaques on the chest.
Fig 2
Fig 2
A, Deep periadnexal lymphoplasmacytic infiltrate. B and C, Vacuolar interface change at the dermoepidermal junction. D, Periodic acid–Schiff stain highlights thickened basement membrane. E, Colloidal iron stain highlights increased mucin in the dermis. (A, B, and C, Hematoxylin-eosin stain; D, periodic acid–Schiff stain; E, colloidal iron stain; original magnifications: A, B, and C, ×100; D and E, ×200.)
Fig 3
Fig 3
A, Punch biopsy specimen with a scant superficial and deep perivascular, periadnexal, and perineural lymphoplasmacytic infiltrate. B, Medium-sized blood vessel at the junction of the dermis and subcutaneous fat with dense granulomatous inflammation permeating the vessel wall and surrounding dermis. C, Atrophic epidermis with a patulous infundibulum, follicular plugging, basal layer vacuolization, and pigment incontinence. D, CD68 highlights histiocytes of the granulomatous vasculitis. (A, B, and C, Hematoxylin-eosin stain; D, CD68 immunohistochemistry stain; original magnifications: A, ×20; B and C, ×100; D, ×200.)
See this image and copyright information in PMC

References

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