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Book

Persistent Postural-Perceptual Dizziness

Brandon Knight  1 , Francisco Bermudez  2 , Carl Shermetaro  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Persistent Postural-Perceptual Dizziness

Brandon Knight et al.
Free Books & Documents

Excerpt

The International Classification of Vestibular Disorders (ICVD) described persistent postural-perceptual dizziness (PPPD) in 2017. Symptoms are portrayed as unsteadiness, dizziness, or non-vertiginous dizziness, which are present most days for 90 days or more and exacerbated by positions such as sitting upright, standing, or walking and visually complex stimuli.

The condition is secondary to disruptions in visual processing and postural control mechanisms. It is classified as a chronic vestibular disorder, although there is an association with conditions such as migraine, anxiety, and depression. It is more common in women than men. Imaging and testing are often unremarkable, and treatment is often multimodal, including cognitive-behavioral therapy, physical therapy, and serotonergic medications.

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Conflict of interest statement

Disclosure: Brandon Knight declares no relevant financial relationships with ineligible companies.

Disclosure: Francisco Bermudez declares no relevant financial relationships with ineligible companies.

Disclosure: Carl Shermetaro declares no relevant financial relationships with ineligible companies.

References

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    1. Azzi JL, Khoury M, Séguin J, Rourke R, Hogan D, Tse D, Lelli DA. Characteristics of persistent postural perceptual dizziness patients in a multidisciplinary dizziness clinic. J Vestib Res. 2022;32(3):285-293. - PubMed
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    1. Holle D, Schulte-Steinberg B, Wurthmann S, Naegel S, Ayzenberg I, Diener HC, Katsarava Z, Obermann M. Persistent Postural-Perceptual Dizziness: A Matter of Higher, Central Dysfunction? PLoS One. 2015;10(11):e0142468. - PMC - PubMed
    1. Li K, Si L, Cui B, Ling X, Shen B, Yang X. Altered spontaneous functional activity of the right precuneus and cuneus in patients with persistent postural-perceptual dizziness. Brain Imaging Behav. 2020 Dec;14(6):2176-2186. - PubMed

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