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. 2022 Jan 18;9(2):33.
doi: 10.3390/vetsci9020033.

Hyperbaric Oxygen Therapy in Systemic Inflammatory Response Syndrome

Débora Gouveia  1   2 , Mariana Chichorro  3 , Ana Cardoso  1 , Carla Carvalho  1 , Cátia Silva  1 , Tiago Coelho  1 , Isabel Dias  3 , António Ferreira  4   5 , Ângela Martins  1   2   5   6
Affiliations

Hyperbaric Oxygen Therapy in Systemic Inflammatory Response Syndrome

Débora Gouveia et al. Vet Sci. .

Abstract

(1) Background: Systemic inflammatory response syndrome (SIRS) can occur due to a large number of traumatic or non-traumatic diseases. Hyperbaric oxygen therapy (HBOT) may be used as a main or adjuvant treatment for inflammation, leading to the main aim of this study, which was to verify the applicability of HBOT as a safe and tolerable tool in SIRS-positive dogs. (2) Methods: This prospective cohort study included 49 dogs who showed two or more parameters of SIRS, divided into the Traumatic Study Group (n = 32) and the Non-Traumatic Study Group (n = 17). All dogs were submitted to HBOT for 60-90 min sessions, with 2.4-2.8 ATA. (3) Results: This study revealed that 73.5% (36/49) of dogs showed improvement, and the minimum number of HBOT sessions was two, with a mean of 12.73. The number of days between diagnosis and the beginning of HBOT showed statistical significance (p = 0.031) relative to the clinical outcome. No dogs showed any major side effects. (4) Conclusions: We concluded that HBOT may be safe and tolerable for SIRS-positive dogs, and that it should be applied as early as possible.

Keywords: ATA; HBOT; SIRS; dogs; traumatic.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Diagram used for the admission of dogs in the clinical study. TSG, Traumatic Study Group; NTSG, Non-Traumatic Study Group; HBOT, Hyperbaric Oxygen Therapy.
Figure 2
Figure 2
Dog placement inside the hyperbaric oxygen chamber.
See this image and copyright information in PMC

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