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Review
. 2022 Feb 10;14(4):885.
doi: 10.3390/cancers14040885.

Cannabidiol (CBD) in Cancer Management

Kylie O'Brien  1   2   3   4
Affiliations
Review

Cannabidiol (CBD) in Cancer Management

Kylie O'Brien. Cancers (Basel). .

Abstract

The plant Cannabis sativa has been in use medicinally for several thousand years. It has over 540 metabolites thought to be responsible for its therapeutic effects. Two of the key phytocannabinoids are cannabidiol (CBD) and tetrahydrocannabinol (THC). Unlike THC, CBD does not have potentially intoxicating effects. Preclinical and clinical research indicates that CBD has a wide range of therapeutic effects, and many of them are relevant to the management of cancer. In this article, we explore some of the potential mechanisms of action of CBD in cancer, and evidence of its efficacy in the integrative management of cancer including the side effects associated with its treatment, demonstrating its potential for integration with orthodox cancer care.

Keywords: cancer; cannabidiol; cannabis; endocannabinoid system; tumours.

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Conflict of interest statement

O’Brien is Chief Medical Officer for Releaf Group Ltd., an Australian company with medical clinics and pharmacies focused on medicinal cannabis, Director of the ICCM Lt (International College of Cannabinoid Medicine), has conducted consultancies for several medicinal cannabis companies, and owns shares in some cannabis companies.

Figures

Figure 1
Figure 1
Integrative Approaches to the Symptoms/Signs Associated with Cancer and its Orthodox Treatment.
See this image and copyright information in PMC

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