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Review
. 2022 Feb 18;11(4):1085.
doi: 10.3390/jcm11041085.

Pancreatic Stone Protein: Review of a New Biomarker in Sepsis

Pedro Fidalgo  1 , David Nora  1   2 , Luis Coelho  1   2 , Pedro Povoa  1   2   3
Affiliations
Review

Pancreatic Stone Protein: Review of a New Biomarker in Sepsis

Pedro Fidalgo et al. J Clin Med. .

Abstract

Sepsis is a life-threatening syndrome characterized by a dysregulated host response to an infection that may evolve rapidly into septic shock and multiple organ failure. Management of sepsis relies on the early recognition and diagnosis of infection and the providing of adequate and prompt antibiotic therapy and organ support. A novel protein biomarker, the pancreatic stone protein (PSP), has recently been studied as a biomarker of sepsis and the available evidence suggests that it has a higher diagnostic performance for the identification of infection than the most used available biomarkers and adds prognostic value. This review summarizes the clinical evidence available for PSP in the diagnosis and prognosis of sepsis.

Keywords: biomarker; infection; pancreatic stone protein; sepsis.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Figure 1
Figure 1
Identification of studies flow diagram.
See this image and copyright information in PMC

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