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Review
. 2022 Jan 26;58(2):188.
doi: 10.3390/medicina58020188.

MDR Tuberculosis Treatment

Juan Espinosa-Pereiro  1   2 , Adrian Sánchez-Montalvá  1   2 , Maria Luisa Aznar  1   2 , Maria Espiau  3
Affiliations
Review

MDR Tuberculosis Treatment

Juan Espinosa-Pereiro et al. Medicina (Kaunas). .

Abstract

Multidrug-resistant (MDR) tuberculosis (TB), resistant to isoniazid and rifampicin, continues to be one of the most important threats to controlling the TB epidemic. Over the last few years, there have been promising pharmacological advances in the paradigm of MDR TB treatment: new and repurposed drugs have shown excellent bactericidal and sterilizing activity against Mycobacterium tuberculosis and several all-oral short regimens to treat MDR TB have shown promising results. The purpose of this comprehensive review is to summarize the most important drugs currently used to treat MDR TB, the recommended regimens to treat MDR TB, and we also summarize new insights into the treatment of patients with MDR TB.

Keywords: MDR; treatment; tuberculosis.

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Conflict of interest statement

The authors have no conflict of interest to declare.

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