Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1978 Mar;57(3):232-8.
doi: 10.1111/j.1600-0404.1978.tb05870.x.

Baclofen trial in six myotonic dystrophy patients

C Guilleminault, W H Flagg, S C Coburn, W C Dement
Clinical Trial

Baclofen trial in six myotonic dystrophy patients

C Guilleminault et al. Acta Neurol Scand. 1978 Mar.

Abstract

Six young adult patients with grade I myotonic dystrophy and a complaint of daytime somnolence underwent 36-hour polygraphic monitoring, dynamometric and electromyographic studies before and under baclofen (60 mg/daily). Patients with the most severe daytime sleepiness had pathologic Sleep Apnea Indexes. After 6 weeks' ingestion of baclofen, no subjective or objective effect on patient symptomatology was found.

PubMed Disclaimer

Publication types

LinkOut - more resources