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Observational Study
. 2022 Feb 24;12(2):e049262.
doi: 10.1136/bmjopen-2021-049262.

Association between multimorbidity, self-rated health and life satisfaction among independent, community-dwelling very old persons in Japan: longitudinal cohort analysis from the Kawasaki Ageing and Well-being Project

Takayuki Ando  1 , Yoshinori Nishimoto  2 , Takumi Hirata  3 , Yukiko Abe  4 , Midori Takayama  5 , Takashi Maeno  6 , Seitaro Fujishima  1 , Toru Takebayashi  7 , Yasumichi Arai  8
Affiliations
Observational Study

Association between multimorbidity, self-rated health and life satisfaction among independent, community-dwelling very old persons in Japan: longitudinal cohort analysis from the Kawasaki Ageing and Well-being Project

Takayuki Ando et al. BMJ Open. .

Abstract

Objective: This study aimed to identify associations between multimorbidity and subjective health outcomes among the very old persons, after adjusting for coexisting conditions such as frailty and depression.

Study setting and participants: This was an observational cross-sectional study involving 1012 independent, community-dwelling very old persons (507 men, 505 women; aged 85-89 years) in Kawasaki city, Japan.

Outcome measures: The primary outcome was the cross-sectional associations between multimorbidity and poor self-rated health (SRH) and life satisfaction using binary logistic regression. The secondary outcome was the association of subjective health with each chronic condition.

Results: The prevalence of multimorbidity (≥2 conditions) was 94.7%, and the average number of chronic conditions was 4.47±1.9. Multimorbidity was significantly associated with poor SRH in the adjusted model only when six or more chronic conditions were present (OR 4.80; 95% CI 1.34 to 17.11; p=0.016). Cerebrovascular disease, heart disease, respiratory disease, connective tissue disease and arthritis showed significant associations with poor SRH after multivariate adjustment. Sex-specific analysis replicated associations between multimorbidity with six or more conditions and SRH in both men and women, while the diseases with the greatest impact on SRH differed between men and women. Most conditions were not associated with low satisfaction with life scale, with the exception of arthritis (OR 1.92, 95% CI 1.32 to 2.78, p=0.001).

Conclusions: Multimorbidity is prevalent in the independent, community-dwelling very old persons and is associated with poor SRH when six or more conditions are present; conditions causing mobility limitations, such as cerebrovascular disease, connective tissue disease and arthritis, have a negative impact on SRH.

Trial registration number: UMIN000026053.

Keywords: epidemiology; general medicine (see internal medicine); geriatric medicine; primary care.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Histogram of the number of comorbid chronic conditions. N, number of participants.
Figure 2
Figure 2
Prevalence of each chronic condition among study population.
See this image and copyright information in PMC

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