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Review
. 1986 May;10(3):165-88.
doi: 10.1007/BF02213979.

Modulation of phagocytic cell function

P A Henricks, J Verhoef, F P Nijkamp
Review

Modulation of phagocytic cell function

P A Henricks et al. Vet Res Commun. 1986 May.

Abstract

Phagocytosis is an important factor in the defense of the host against all kinds of microorganisms. The process of phagocytosis of microorganisms by phagocytes can be separated into distinct but interrelated phases: adherence, chemotaxis, opsonization, attachment, ingestion, degranulation and killing. Phagocytosis is accompanied by an increase in oxygen metabolism in which H2O2 and activated oxygen species are generated. Modulation of phagocytic cell function can be brought about by a variety of substances. Microorganisms produce and contain components which influence the process of phagocytosis. Surrounding tissue cells and the phagocytes themselves produce biologically active molecules that modulate phagocytosis.

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