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Comment
. 2022 Jan 1;234(1):97-98.
doi: 10.1097/XCS.0000000000000007.

Fibrinolysis Shutdown in Severe COVID-19: Highly Prevalent but not Independently Predictive of Thrombosis or Poorer Outcomes

James Littlejohn  1 , Ljiljana V Vasovic, Melissa M Cushing, Philip S Barie
Affiliations
Comment

Fibrinolysis Shutdown in Severe COVID-19: Highly Prevalent but not Independently Predictive of Thrombosis or Poorer Outcomes

James Littlejohn et al. J Am Coll Surg. .
No abstract available

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References

    1. Meisozo JP, Moore HB, Moore EE. Fibrinolysis shutdown in COVID-19: clinical manifestations, molecular mechanisms, and therapeutic implications. J Am Coll Surg. 2021;232:e995–e1003.
    1. Moore HB, Moore EE, Liras IN, et al. Acute fibrinolysis shutdown after injury occurs frequently and increases mortality: a multicenter evaluation of 2,540 severely injured patients. J Am Coll Surg. 2016;222:e347–e355.
    1. Gomez-Builes JC, Acuna SA, Nascimento B, et al. Harmful or physiologic: diagnosing fibrinolysis shutdown in a trauma cohort with rotational thromboelastometry. Anesth Analg. 2018;127:840–849.
    1. Creel-Bulos C, Sniecinski R. Fibrinolysis shutdown and thrombosis in a COVID-19 ICU. Shock. 2021;55:845–846.
    1. Kruse JM, Magomedov A, Kurreck A, et al. Thromboembolic complications in critically ill COVID-19 patients are associated with impaired fibrinolysis. Crit Care. 2020;24:676.

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