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. 2022 Sep 30;75(7):1242-1244.
doi: 10.1093/cid/ciac162.

Circulation of an Artemisinin-Resistant Malaria Lineage in a Traveler Returning from East Africa to France

Romain Coppée  1 , Justine Bailly  1   2 , Véronique Sarrasin  1   2 , Bertin Vianou  3 , Boris Enock Zinsou  3 , Edith Mazars  4 , Hugues Georges  5 , Samia Hamane  6 , Rose Anne Lavergne  7 , Eric Dannaoui  8 , Betty Balikagala  9 , Naoyuki Fukuda  9 , Emmanuel I Odongo-Aginya  10 , Toshihiro Mita  9 , Sandrine Houzé  1   2 , Jérôme Clain  1   2
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Circulation of an Artemisinin-Resistant Malaria Lineage in a Traveler Returning from East Africa to France

Romain Coppée et al. Clin Infect Dis. .

Abstract

A returned traveler to Uganda presented with a Plasmodium falciparum kelch13 A675V mutant infection that exhibited delayed clearance under artesunate therapy. Parasites were genetically related to recently reported Ugandan artemisinin-resistant A675V parasites. Adequate malaria prevention measures and clinical and genotypic surveillance are important tools to avoid and track artemisinin resistance.

Keywords: Plasmodium falciparum; East Africa; artemisinin resistance; kelch13; whole-genome sequencing.

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Conflict of interest statement

Potential conflicts of interest. All authors: No reported conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest.

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