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Review
. 2022 Feb 11;10(2):279.
doi: 10.3390/vaccines10020279.

Multiple Sclerosis Patients and Disease Modifying Therapies: Impact on Immune Responses against COVID-19 and SARS-CoV-2 Vaccination

Maryam Golshani  1 , Jiří Hrdý  1
Affiliations
Review

Multiple Sclerosis Patients and Disease Modifying Therapies: Impact on Immune Responses against COVID-19 and SARS-CoV-2 Vaccination

Maryam Golshani et al. Vaccines (Basel). .

Abstract

This article reviews the literature on SARS-CoV-2 pandemic and multiple sclerosis (MS). The first part of the paper focuses on the current data on immunopathology of SARS-CoV-2 and leading vaccines produced against COVID-19 infection. In the second part of the article, we discuss the effect of Disease Modifying Therapies (DMTs) on COVID-19 infection severity or SARS-CoV-2 vaccination in MS patients plus safety profile of different vaccine platforms in MS patients.

Keywords: COVID-19; DMTs; SARS-CoV-2; immunosuppression; multiple sclerosis; vaccine.

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Conflict of interest statement

The authors declare no conflict of interest.

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