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Review
. 2022 Mar;17(1):41-52.
doi: 10.1016/j.jsmc.2021.10.006.

Disrupted Sleep During a Pandemic

Niraj Kumar  1 , Ravi Gupta  2
Affiliations
Review

Disrupted Sleep During a Pandemic

Niraj Kumar et al. Sleep Med Clin. 2022 Mar.

Abstract

The COVID-19 pandemic affected sleep in several people. Though most of the studies argued that age, gender, employment, finances, responsibilities, and exposure to sunlight governed sleep-wake schedule and sleep disturbances, there is also scientific evidence to suggest that these issues could have aroused because of the infiltration of the central nervous system (CNS) by SARS-CoV-2. Sleep disturbances must be addressed during the pandemic as sleep disturbances and systemic inflammation run in a vicious cycle; quality of sleep and timing of vaccination can influence the immune response to vaccination and subjects having obstructive sleep apnea (OSA) are at higher risk for having SARS-CoV-2 infection-related complications.

Keywords: COVID-19; Insomnia; Poor quality sleep; SARS-CoV-2 infection; Sleep.

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Conflict of interest statement

Disclosure The authors have nothing to disclose.

Figures

Fig. 1
Fig. 1
Pathophysiology of sleep disruption during the COVID-19 pandemic. ACE-2 “R”, angiotensin-converting enzyme-2 receptor; ANS, autonomic nervous system; BBB, blood-brain barrier; CNS, central nervous system; COVID-19, coronavirus disease 2019; Dec., decreased; HC, home confinement; HPA, hypothalamic-pituitary-adrenal axis; Inc., increased; MS, multiple sclerosis; NEP, norepinephrine; NK cells, natural killer cells; NL, narcolepsy; OSA, obstructive sleep apnea; PD, Parkinson disease.
See this image and copyright information in PMC

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