A new sophistication for breast cancer PDXs

Neil Portman^{1

2}, Elgene Lim^{3

4}

Affiliations

¹ Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
² Faculty of Medicine, St. Vincent's Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
³ Garvan Institute of Medical Research, Sydney, New South Wales, Australia. e.lim@garvan.org.au.
⁴ Faculty of Medicine, St. Vincent's Clinical School, University of New South Wales, Sydney, New South Wales, Australia. e.lim@garvan.org.au.

PMID: 35221337
DOI: 10.1038/s43018-021-00328-z

Comment

A new sophistication for breast cancer PDXs

Neil Portman et al. Nat Cancer. 2022 Feb.

. 2022 Feb;3(2):138-140.

doi: 10.1038/s43018-021-00328-z.

Authors

Neil Portman^{1

2}, Elgene Lim^{3

4}

Affiliations

¹ Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
² Faculty of Medicine, St. Vincent's Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
³ Garvan Institute of Medical Research, Sydney, New South Wales, Australia. e.lim@garvan.org.au.
⁴ Faculty of Medicine, St. Vincent's Clinical School, University of New South Wales, Sydney, New South Wales, Australia. e.lim@garvan.org.au.

PMID: 35221337
DOI: 10.1038/s43018-021-00328-z

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A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology.
Guillen KP, Fujita M, Butterfield AJ, Scherer SD, Bailey MH, Chu Z, DeRose YS, Zhao L, Cortes-Sanchez E, Yang CH, Toner J, Wang G, Qiao Y, Huang X, Greenland JA, Vahrenkamp JM, Lum DH, Factor RE, Nelson EW, Matsen CB, Poretta JM, Rosenthal R, Beck AC, Buys SS, Vaklavas C, Ward JH, Jensen RL, Jones KB, Li Z, Oesterreich S, Dobrolecki LE, Pathi SS, Woo XY, Berrett KC, Wadsworth ME, Chuang JH, Lewis MT, Marth GT, Gertz J, Varley KE, Welm BE, Welm AL. Guillen KP, et al. Nat Cancer. 2022 Feb;3(2):232-250. doi: 10.1038/s43018-022-00337-6. Epub 2022 Feb 24. Nat Cancer. 2022. PMID: 35221336 Free PMC article.

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References

1. Woo, X. Y. et al. Nat. Genet. 53, 86–99 (2021). - DOI
1. Bruna, A. et al. Cell 167, 260–274.e222 (2016). - DOI
1. DeRose, Y. S. et al. Nat. Med. 17, 1514–1520 (2011). - DOI
1. Sachs, N. et al. Cell 172, 373–386.e310 (2018). - DOI
1. Guillen, K. P. et al. Nat. Cancer https://doi.org/10.1038/s43018-022-00337-6 (2021).

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A new sophistication for breast cancer PDXs

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A new sophistication for breast cancer PDXs

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