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Review
. 2022 Mar;38(2):167-172.
doi: 10.1007/s12055-021-01269-z. Epub 2022 Jan 3.

Pulmonary sclerosing pneumocytoma-a case series

Nishok David  1 , Sujith Thomas Chandy  2 , Santhosh Regini Benjamin  1 , Aamir Mohammad  1 , Sameer Mallampati  1 , Thomas Alex Kodiatte  3 , Birla Roy Gnanamuthu  1
Affiliations
Review

Pulmonary sclerosing pneumocytoma-a case series

Nishok David et al. Indian J Thorac Cardiovasc Surg. 2022 Mar.

Abstract

Pulmonary sclerosing pneumocytoma (PSP) is a rare and interesting pulmonary tumour that presents a diagnostic challenge to the surgeon due to its bland symptomatology, indolent course, non-specific radiological features and ambiguous histopathological findings, which could lead to errors in management and prognostication. Herein, we present a series of 4 patients with PSP who were managed in our institution over a period of 8 years and briefly discuss relevant literature.

Keywords: Benign or congenital lesions; Carcinoid; Immunohistochemistry; Lung; Sclerosing pneumocytoma; Tumour.

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Conflict of interest statement

Conflict of interestThe authors declare no competing interests.

Figures

Fig. 1
Fig. 1
a Case 1: CT thorax coronal section showing the PSP with calcification, secondary nodules (left arrows), and the overlying vessel sign (right arrows). b CT thorax axial section showing PSP with secondary nodules (left arrows), halo sign (double arrows), and air-gap sign (thick arrow). c Gross specimen of tumour showing areas of calcification and congestion, secondary nodules (left arrows), and a rim of compressed lung parenchyma (right arrows)
Fig. 2
Fig. 2
IHC stains of PSP. a CK immunostaining of the lining cells (100 ×). b 400 × magnification of the CK stain. c TTF1 immunostaining of the lining and stromal cells (100 ×). d 400 × magnification of TTF1 staining
Fig. 3
Fig. 3
Microphotograph of the typical carcinoid (asterisk) adjacent to the PSP (black arrow). Hematoxylin and eosin staining, 4 × magnification
Fig. 4
Fig. 4
a Case 4: CT scan of the thorax, axial section, showing a left lower lobe PSP with the pseudo-capsule sign (left arrows) and overlying vessel sign (right arrows). b Bisected gross specimen showing compressed lung parenchymal tissue which corresponds to the pseudo-capsule sign
See this image and copyright information in PMC

References

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