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Randomized Controlled Trial
. 2022 Feb 18:2022:6192190.
doi: 10.1155/2022/6192190. eCollection 2022.

The Value of Gastric Cancer Staging by Endoscopic Ultrasonography Features in the Diagnosis of Gastroenterology

Hua Zhou  1 , Min Li  1
Affiliations
Randomized Controlled Trial

The Value of Gastric Cancer Staging by Endoscopic Ultrasonography Features in the Diagnosis of Gastroenterology

Hua Zhou et al. Comput Math Methods Med. .

Retraction in

Abstract

This research was aimed at exploring the application value of endoscopic ultrasonography (EUS) in the diagnosis of gastric cancer staging and the correlation between staging and clinical features of gastric cancer. A total of 72 patients with gastric cancer were selected and randomly divided into two groups. The patients in the pathological group underwent postoperative pathological examination, while those in the EUS group received preoperative EUS examination. The results showed that the staging accuracy of EUS was 73.33% for T1, 78.57% for T2, 27% for T3, and 100% for T4, compared with the pathological staging. The accuracy of N- and N+ was 42.5% and 82.3% in EUS, respectively, and the total accuracy was 55.7%. There was no considerable difference in the accuracy of T staging between early gastric cancer and advanced gastric cancer (P > 0.05), but there was a considerable difference in N staging (P < 0.05). Lymph node metastasis affected the accuracy of N staging (P < 0.05). The number and location of metastatic lymph nodes did not affect the judgment of metastatic lymph nodes (P > 0.05). In addition, the proportion of understaging and overstaging was greatly different among different lesion sizes and histological types of gastric cancer (P < 0.05). To sum up, the accuracy of EUS for T and N staging of gastric cancer needed to be improved. The location of gastric cancer lesions affected the accuracy of T staging, while the depth of invasion and lymph node metastasis affected the accuracy of N staging.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
EUS manifestations of different T stages of gastric cancer: (a) T1 stage gastric cancer: the tumor invaded the submucosa; (b) T2 stage gastric cancer: the tumor invaded the muscularis propria; (c) T3 stage gastric cancer: where the tumor broke through the serosal layer; (d) T4 stage gastric cancer: where the tumor broke through the serosal layer and was closely related to the pancreas.
Figure 2
Figure 2
Regional lymph node metastases under EUS. (Several fused and enlarged lymph nodes about 1 cm in diameter were found, and N was the metastatic lymph node.)
Figure 3
Figure 3
Basic information of the patients.
Figure 4
Figure 4
EUS and pathological T and N staging results.
Figure 5
Figure 5
Evaluation of EUS staging results.
Figure 6
Figure 6
Accuracy of T staging under EUS.
Figure 7
Figure 7
Comparison of EUS and pathological N staging results.
Figure 8
Figure 8
The influence of gastric cancer invasion depth and lymph node metastasis on EUS staging. (Compared with different depth of invasion, ∗P < 0.05; compared with different degree of lymph node metastasis, #P < 0.05.)
Figure 9
Figure 9
Staging accuracy of different lesions under EUS. (Compared with cardia, ∗P < 0.05.)
See this image and copyright information in PMC

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