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Review
. 2022 Jan 27:2022:6699596.
doi: 10.1155/2022/6699596. eCollection 2022.

Impact of Material and Lens Design on Repositioning Surgery of Toric Intraocular Lenses: A Single-Arm Meta-Analysis

Jing Wu  1   2 , Changping Yang  3 , Yan Yin  4 , Linlin Liu  5 , Hui Wang  5
Affiliations
Review

Impact of Material and Lens Design on Repositioning Surgery of Toric Intraocular Lenses: A Single-Arm Meta-Analysis

Jing Wu et al. J Ophthalmol. .

Abstract

Aim: To analyze the pooled incidence rate in repositioning surgery by considering different materials and designs.

Methods: All published studies investigating the repositioning surgery of toric intraocular lenses (IOLs) before September 1, 2020, were searched and evaluated. The R3.5.2 software was used to extract the data, and a single arm meta-analysis was performed.

Results: 19 cases from 18 published studies articles were included in the meta-analysis. The pooled incidence rate in repositioning surgery was 2% (I 2 = 53%, P heterogeneity<0.01). Plate and silicone IOLs had significantly higher incidence rates (6% for each) than loop (2%) and hydrophobic acrylate (2%). Incidence rates of Acrysof, Staar, TECNIS, PhysIOL SA, T-flex 623T, and Microsil 6116TU groups were 1% (95% CI [1%-2%]), 6% (95% CI [4%-9%]), 3% (95% CI [2%-4%]), 1.40% (1/71), 3.03% (1/33), and 4.76% (1/21), respectively.

Conclusions: The pooled incidence rate of repositioning surgery in IOLs was 2%. Materials and designs would be risk factors for the rotational stability of the toric IOLs. Pooled incidence rates of the hydrophobic acrylate and loop group were lower than those of the silicone and plate group. Product identity is the main driver of heterogeneity.

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Conflict of interest statement

All authors of this manuscript declare that there are no conflicts of interest and have no financial relationship with organizations.

Figures

Figure 1
Figure 1
Flowchart demonstrating how the identified published studies were included in the meta-analysis.
Figure 2
Figure 2
The forest plot displaying the pooled incidence rate of repositioning surgery of toric IOL.
Figure 3
Figure 3
The forest plots displaying the pooled incidence rate of repositioning surgery of (a) loop-haptic toric IOLs and (b) plate-haptic IOLs.
Figure 4
Figure 4
The forest plots displaying the pooled incidence rate of repositioning surgery of (a) hydrophobic acrylic material IOLs and (b) silicone material IOLs.
Figure 5
Figure 5
The forest plots displaying the pooled incidence rate of repositioning surgery of (a) Acrysof toric IOLs, (b) Staar IOLs, and (c) TECNIS toric IOLs.
Figure 6
Figure 6
(a) The funnel plot displaying the pooled incidence rate of repositioning surgery of toric IOLs. (b) The filled funnel plot with pseudo-95% CI (the pseudo-95% confidence interval (CI) is computed as part of the analysis that produces the funnel plot).
See this image and copyright information in PMC

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