What Are Adaptive Platform Clinical Trials and What Role May They Have in Cardiovascular Medicine?

Patrick R Lawler^{1

2}, Judith S Hochman³, Ryan Zarychanski^{4

5}

Affiliations

¹ Peter Munk Cardiac Centre, Toronto General Hospital, Canada (P.R.L.).
² Division of Cardiology and Interdepartmental Division of Critical Care Medicine, University of Toronto, Canada (P.R.L.).
³ Cardiovascular Clinical Research Center and Division of Cardiology, New York University Langone Health, New York University Grossman School of Medicine (J.S.H.).
⁴ University of Manitoba, Max Rady College of Medicine, Department of Internal Medicine, Sections of Hematology/Medical Oncology and Critical Care, Winnipeg, Canada (R.Z).
⁵ CancerCare Manitoba, Department of Medical Oncology and Hematology, Winnipeg, Canada (R.Z.).

Patrick R Lawler et al. Circulation. 2022 Mar.

. 2022 Mar;145(9):629-632.

doi: 10.1161/CIRCULATIONAHA.121.058113. Epub 2022 Feb 28.

Patrick R Lawler^{1

2}, Judith S Hochman³, Ryan Zarychanski^{4

5}

¹ Peter Munk Cardiac Centre, Toronto General Hospital, Canada (P.R.L.).
² Division of Cardiology and Interdepartmental Division of Critical Care Medicine, University of Toronto, Canada (P.R.L.).
³ Cardiovascular Clinical Research Center and Division of Cardiology, New York University Langone Health, New York University Grossman School of Medicine (J.S.H.).
⁴ University of Manitoba, Max Rady College of Medicine, Department of Internal Medicine, Sections of Hematology/Medical Oncology and Critical Care, Winnipeg, Canada (R.Z).
⁵ CancerCare Manitoba, Department of Medical Oncology and Hematology, Winnipeg, Canada (R.Z.).

No abstract available

Keywords: COVID-19; adaptive clinical trial; clinical trial; thrombosis.

MeSH terms