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Case Reports
. 2022 Feb 24;10(2):e05467.
doi: 10.1002/ccr3.5467. eCollection 2022 Feb.

Remdesivir for COVID-19 pneumonia in patients with severe chronic kidney disease: A Case series and review of the literature

Ahmad Al Bishawi  1 , Hamad Abdel Hadi  1 , Eman Elmekaty  2 , Musaed Al Samawi  1 , Arun Nair  1 , Mohammed Abou Kamar  1 , Muna Al Maslamani  1 , Alaaeldin Abdelmajid  1
Affiliations
Case Reports

Remdesivir for COVID-19 pneumonia in patients with severe chronic kidney disease: A Case series and review of the literature

Ahmad Al Bishawi et al. Clin Case Rep. .

Abstract

Remdesivir was the first antiviral agent to receive FDA authorization for severe COVID-19 management, which restricts its use with severe renal impairment due to concerns that active metabolites might accumulate, causing renal toxicities. With limited treatment options, available evidence on such patient groups is important to assess for future safety.

Keywords: COVID‐19; SARS‐CoV‐2; chronic kidney diseases (CKD); remdesivir.

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Conflict of interest statement

No conflict of interest declared by authors.

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