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Review
. 2023 Feb;192(1):115-123.
doi: 10.1007/s11845-022-02938-7. Epub 2022 Mar 1.

Colchicine-regeneration of an old drug

Aoife Casey  1 , Sandra Quinn  2 , Brendan McAdam  2 , Mark Kennedy  2 , Richard Sheahan  2
Affiliations
Review

Colchicine-regeneration of an old drug

Aoife Casey et al. Ir J Med Sci. 2023 Feb.

Abstract

Immunomodulation by colchicine is a well-established therapy for targeting inflammatory pathways in gout, pericarditis and Behchet's disease. In more recent times, evidence has emerged demonstrating a potential role for colchicine in several cardiac conditions. This article aims to summarise the evidence behind the established guidelines for use of low-dose colchicine in pericarditis and examine the evolving evidence for its use in cardiovascular disease and most recently COVID-19.

Keywords: Atherosclerosis; COVID-19; Cardiovascular disease; Colchicine; Pericarditis.

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Conflict of interest statement

The authors declare no competing interests.

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