Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Feb;8(1):25-30.
doi: 10.20407/fmj.2020-027. Epub 2021 Mar 20.

Risk factors for epiretinal membrane surgery after initial pars plana vitrectomy for rhegmatogenous retinal detachment

Yuki Takamidou  1 , Tadashi Mizuguchi  1 , Ryouta Sakurai  1 , Mitsuo Sugimoto  1 , Atsuhiro Tanikawa  1 , Masayuki Horiguchi  1
Affiliations

Risk factors for epiretinal membrane surgery after initial pars plana vitrectomy for rhegmatogenous retinal detachment

Yuki Takamidou et al. Fujita Med J. 2022 Feb.

Abstract

Objectives: The purpose of this study was to examine the incidence of, and risk factors for, epiretinal membrane (ERM) surgery after an initial pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD).

Methods: The records of consecutive patients (3,495 eyes of 3,387 patients) who underwent RRD repair at Fujita Health University Hospital between January 1, 2008, and February 28, 2019, were retrospectively reviewed. A total of 1,736 eyes without an ERM in preoperative optical coherence tomography were included in this study.

Results: The incidence of ERM surgery after RRD repair was 2.4%. The mean time from RRD repair to ERM surgery was 19.5±27.2 months. The odds ratios after adjusting for age and sex were as follows: the preoperative visual acuity (logarithm of the minimum angle of resolution, logMAR), 2.17 (p=0.02; 95% confidence interval [CI], 1.11-5.16); axial length, 1.38 (p=0.002; 95% CI, 1.12-1.72); 20-gauge vitreous surgery instruments, 3.82 (p<0.0001; 95% CI, 2.02-7.16); internal limiting membrane (ILM) peeling, 0.28 (p=0.033; 95% CI, 0.05-0.92). ERM surgery improved visual acuity from 0.36 to 0.01 logMAR, even at ≥1.5 years after RRD repair.

Conclusions: Careful follow-up is required in the following cases: long axial length before RRD repair, low visual acuity, use of 20-gauge vitreous surgery instruments, and a lack of ILM peeling.

Keywords: Epiretinal membrane surgery; Pars plana vitrectomy; Retinal detachment; Rhegmatogenous retinal detachment; Risk factors.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Inclusion and exclusion criteria
Figure 2
Figure 2
Box plot showing the comparison between best-corrected visual acuity (logMAR) values before and after epiretinal membrane (ERM) surgery
See this image and copyright information in PMC

References

    1. Wilkinson CP. Visual results following scleral buckling for retinal detachments sparing the macula. Retina 1981; 1: 113–116. - PubMed
    1. McCarty DJ, Mukesh BN, Chikani V, Wang JJ, Mitchell P, Taylor HR, McCarty CA. Prevalence and associations of epiretinal membranes in the visual impairment project. Am J Ophthalmol 2005; 140: 288–294. - PubMed
    1. Mitchell P, Smith W, Chey T, Wang JJ, Chang A. Prevalence and associations of epiretinal membranes. The Blue Mountains Eye Study, Australia. Ophthalmology 1997; 104: 1033–1040. - PubMed
    1. Avila MP, Trempe CL, Kozlowski JM, Jalkh AE, Takahashi M, Schepens CL. Biomicroscopic study of the vitreous in eyes with macular pucker after retinal detachment surgery. Ann Ophthalmol 1985; 17: 403–410. - PubMed
    1. Clarkson JG, Green WR, Massof D. A histopathologic review of 168 cases of preretinal membrane. Am J Ophthalmol 1977; 84: 1–17. - PubMed