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. 2022 Jun;80(7):1135-1137.
doi: 10.1111/his.14636. Epub 2022 Mar 29.

Primary uterine synovial sarcoma with SMARCA4 loss

Jennifer Pors  1   2 , Kelly A Devereaux  1 , Daniella Hildebrandt  1 , Teri A Longacre  1
Affiliations

Primary uterine synovial sarcoma with SMARCA4 loss

Jennifer Pors et al. Histopathology. 2022 Jun.
No abstract available

Keywords: BRG1; SMARCA4; sarcoma; synovial sarcoma; uterus.

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References

    1. World Health Organisation (WHO) Classification of Tumours Editorial Board. WHO classification of tumours soft tissue and bone tumours. 5th ed. Lyon: IARC Press, 2020.
    1. Kolin DL, Dong F, Maltay M et al. SMARCA4-deficient undifferentiated uterine sarcoma (malignant rhabdoid tumor of the uterus): a clinicopathologic entity distinct from undifferentiated carcinoma. Mod. Pathol. 2018; 31; 1442-1456.
    1. Ramalingam P, Croce S, McCluggage WG. Loss of expression of SMARCA4 (BRG1), SMARCA2 (BRM) and SMARCB1 (INI1) in undifferentiated carcinoma of the endometrium is not uncommon and is not always associated with rhabdoid morphology. Histopathology 2017; 70; 359-366.
    1. Strehl JD, Wachter DL, Fiedler J et al. Pattern of SMARCB1 (INI1) and SMARCA4 (BRG1) in poorly differentiated endometrioid adenocarcinoma of the uterus: analysis of a series with emphasis on a novel SMARCA4-deficient dedifferentiated rhabdoid variant. Ann. Diagn. Pathol. 2015; 19; 198-202.
    1. Karnezis AN, Wang Y, Ramos P et al. Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type. J. Pathol. 2016; 238; 389-400.

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