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. 2023 Apr;29(2):165-171.
doi: 10.1177/15910199221081249. Epub 2022 Mar 2.

Comparison of Solitaire and Neuroform Stenting for Coiling of Intracranial Bifurcation Aneurysms

Hailin Wan  1 , Gang Lu  1 , Lei Huang  1 , Liang Ge  1 , Yeqing Jiang  1 , Xiaolong Zhang  1
Affiliations

Comparison of Solitaire and Neuroform Stenting for Coiling of Intracranial Bifurcation Aneurysms

Hailin Wan et al. Interv Neuroradiol. 2023 Apr.

Abstract

Purpose: To compare the technical performance and outcomes of Solitaire and Neuroform stents for treatment of intracranial bifurcation aneurysms (IBAs).

Methods: IBAs treated by stent-assisted coiling using a Solitaire or Neuroform stent between October 2010 and December 2019 were retrospectively evaluated. Patient demographics, aneurysm information, treatment technique, periprocedural and device-related complications, parent artery angle change, along with initial and follow-up angiographic results were analyzed.

Results: One hundred twenty-one patients with 121 IBAs treated with Solitaire (n = 101) or Neuroform (n = 20) stent-assisted coiling were included. Aneurysm size, thrombotic and hemorrhagic complication rate, initial occlusion rate and in-stent stenosis between the two cohorts were not significantly different. Aneurysm location was significantly different between the two groups (p = 0.032). Jailing technique rate for coiling was significantly higher in the Solitaire than the Neuroform group (70.3% vs. 35.0%, p < 0.01). Follow-up DSA demonstrated a significantly lower recurrence rate for the Solitaire cohort (2.9% vs. 22.2%, p = 0.016). Parent artery angle changes, immediately post-operative and on follow-up were significantly greater in the Solitaire stent group (p < 0.05).

Conclusions: For intracranial bifurcation aneurysms, Solitaire stent-assisted coiling achieved a significantly lower recurrence rate and induced more favorable parent artery angular remodeling than Neuroform stenting.

Keywords: Neuroform; Solitaire; embolization; intracranial bifurcation aneurysm.

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Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Flow chart of the study population. IBANs, intracranial bifurcation aneurysms; SAC, stent-assisted coiling.
Figure 2.
Figure 2.
Schematic drawing illustrating the measurement of the parent artery angle, pre-treatment (A) and post-operation (B).
Figure 3.
Figure 3.
A middle cerebral artery bifurcation aneurysm (A) obliterated with Solitaire stent-assisted coiling (B); 7-month follow-up angiography showed no recurrence (C).
Figure 4.
Figure 4.
An anterior communicating artery aneurysm (A) treated with Neuroform stent-assisted coiling (B); 10-month follow-up angiography confirmed no recurrence (C).
See this image and copyright information in PMC

References

    1. Chalouhi N, Hoh BL, Hasan D. Review of cerebral aneurysm formation, growth, and rupture. Stroke 2013;44:3613–3622. - PubMed
    1. Baharoglu MI, Lauric A, Safain MGet al. et al. Widening and high inclination of the middle cerebral artery bifurcation Are associated With presence of aneurysms. Stroke 2014;45:2649–2655. - PMC - PubMed
    1. Can A, Ho AL, Dammers Ret al. et al. Morphological parameters associated with middle cerebral artery aneurysms. Neurosurgery 2015;76:721–726; discussion 726-727. - PubMed
    1. Zhang XJ, Gao BL, Hao WLet al. et al. Presence of anterior communicating artery aneurysm Is associated With Age, bifurcation angle, and vessel diameter. Stroke 2018;49:341–347. - PubMed
    1. Song J, Zhu F, Qian Y, et al. Morphological and hemodynamic differences between aneurysmal middle cerebral artery bifurcation and contralateral nonaneurysmal anatomy. Neurosurgery 2017;81:779–786. - PubMed