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. 2022 May;21(5):1822-1829.
doi: 10.1111/jocd.14893. Epub 2022 Mar 14.

Acro-ischemic lesions in COVID-19 patients: A case series

Rafet Ozbey  1 , Mehmet Fatih Algan  2
Affiliations

Acro-ischemic lesions in COVID-19 patients: A case series

Rafet Ozbey et al. J Cosmet Dermatol. 2022 May.

Abstract

COVID-19 is a systemic disease characterized by vascular damage, increased inflammation, and hypercoagulability. Acral ischemic lesions occur as a result of increased inflammation and cutaneous thrombosis. Skin lesions can sometimes be the only symptom of COVID-19. In this respect, recognizing acro-ischemic lesions, which are skin lesions, may help in the early diagnosis of the disease and in predicting the prognosis. In patients with skin lesions without typical symptoms, the diagnosis of COVID-19 should be kept in mind. Herein, we describe five patients affected by COVID-19 which developed acro-ischemic lesions.

Keywords: COVID-19; acro-ischemia; leukocytoclastic vasculitis; livedo; penis necrosis; skin necrosis; thrombosis.

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Conflict of interest statement

The authors declare no conflict of interests.

Figures

FIGURE 1
FIGURE 1
Clinical views of case 1. (A) livedoid lesion on the right hand (1st day). (B) hemorrhagic bulla on the sole of the right foot (9th day). (C,D) lesion that started as palpable purpura and ended with necrotic bullae on the lower extremities (16th day). (E,F,G,H) skin necrosis on the lower extremities (32th day). (I,J) necrosis on distal of the right and left hand finger (19th day). (The day of onset of symptoms was accepted as day 1)
FIGURE 2
FIGURE 2
Clinical views of case 2. (A,B) circular skin necrosis on the right lower extremity. (C) necrosis on the right foot first and second toe tips necrosis
FIGURE 3
FIGURE 3
Clinical views of case 3. (A,B) necrosis on the left hand second finger and distal of right first toe
FIGURE 4
FIGURE 4
Clinical views of case 4 (A,B) Postoperative image of the necrotic right hand fingers 1,2,3, and 5. (C) necrosis of the glans penis
FIGURE 5
FIGURE 5
Clinical view of case 5, necrosis on the distal of right hand fifth finger
See this image and copyright information in PMC

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