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. 2022 Feb;33(2):95-102.
doi: 10.5152/tjg.2021.201154.

OLGA- and OLGIM-Based Staging in the Patients with Gastritis and Endoscopy Indications

Fariborz Mansour-Ghanaei  1 , Farahnaz Joukar  2 , Sara Yeganeh  3 , Mahbobeh Sadeghi  3 , Arash Daryakar  4 , Masood Sepehrimanesh  5
Affiliations

OLGA- and OLGIM-Based Staging in the Patients with Gastritis and Endoscopy Indications

Fariborz Mansour-Ghanaei et al. Turk J Gastroenterol. 2022 Feb.

Abstract

Background: Gastric cancer is one of the most common cancers with high mortality. In Iran, the high-risk regions include Northern and Northwestern parts. The aim of this study was to assess the operative link on gastritis assessment- and operative link on gastric intestinal metaplasia-based staging in patients with upper gastrointestinal symptoms.

Methods: Totally, 345 patients underwent upper gastrointestinal endoscopy. Also, the status of Helicobacter pylori infection was evaluated using rapid urease test and histological method. Moreover, histological changes were assessed using the Update Sydney System. The operative link on gastritis assessment- and operative link on gastric intestinal metaplasia-based stages of 0-II were considered as low-risk stages and stages III and IV were considered as high-risk stages.

Results: Most of the patients were lower than 60 years (245 patients, 71%), and 71.9% of our patients had H. pylori infection. The frequency of atrophic gastritis and intestinal metaplasia was 44.9% and 25.2%, respectively (P < .001). Eleven patients (73.7%) with gastric adenocarcinoma had a low risk and 2 patients with low-grade dysplasia had a high risk of operative link on gastritis assessment and operative link on gastric intestinal metaplasia. Almost, 62.5% of gastric cancer patients with an intestinal type of gastric adenocarcinoma were at low-risk stages.

Conclusions: Although high stages of operative link on gastritis assessment and operative link on gastric intestinal metaplasia need further follow-up, lower stages of atrophy or intestinal metaplasia also require follow-up. Furthermore, operative link on gastritis assessment method in detecting a greater number of patients who need follow-up is more successful and profitable.

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Conflict of interest statement

Conflict of Interest: The authors have no conflict of interest to declare.

Figures

Figure 1.
Figure 1.
The place of obtained biopsy samples from dyspeptic patients.
Figure 2.
Figure 2.
Percentage of patients with atrophic gastritis based on OLGA staging and intestinal metaplasia based on OLGIM staging in different age categories.
Figure 3.
Figure 3.
The frequency of patients with and without H. Pylori infection based on age, the cause of referral, endoscopic and pathological findings. Black bar, positive infection; White bar, negative infection.
See this image and copyright information in PMC

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References

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