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. 2022 Apr;22(4):445-446.
doi: 10.1016/S1473-3099(22)00135-9. Epub 2022 Feb 28.

Durability of omicron-neutralising serum activity after mRNA booster immunisation in older adults

Kanika Vanshylla  1 , Pinkus Tober-Lau  2 , Henning Gruell  1 , Friederike Münn  2 , Ralf Eggeling  3 , Nico Pfeifer  4 , N Han Le  2 , Irmgard Landgraf  5 , Florian Kurth  6 , Leif E Sander  2 , Florian Klein  7
Affiliations

Durability of omicron-neutralising serum activity after mRNA booster immunisation in older adults

Kanika Vanshylla et al. Lancet Infect Dis. 2022 Apr.
No abstract available

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Conflict of interest statement

KV, HG, and FKl are listed as inventors on patent applications regarding SARS-CoV-2-neutralising antibodies filed by the University of Cologne. All other authors declare no competing interests. KV, PT-L, and HG contributed equally. FKu, LES, and FKl contributed equally. Acknowledgments are listed in the appendix (p 7).

Figures

Figure
Figure
Longitudinal assessment of SARS-CoV-2-neutralising serum activity in older adults Wu01-neutralising, delta-neutralising, and omicron-neutralising serum 50% geometric mean inhibitory serum dilutions (serum ID50) determined using pseudovirus neutralisation assays for 37 individuals. Lines connect study visits (visit 1 to 4) for each individual. Grey areas indicate booster administration period. Dotted lines show lower limit of quantification.
See this image and copyright information in PMC

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