PYW reports research support from Agios, AstraZeneca/MedImmune, Bayer, Celgene, Eli Lilly, Genentech/Roche, Kazia Therapeutics, MediciNova, Merck, Novartis, Nuvation Bio, Oncoceutics, Vascular Biogenics, and VBI Vaccines; and has an advisory or board member role in Agios, AstraZeneca, Bayer, Black Diamond, Boston Pharmaceuticals, ElevateBio, Imvax, Karyopharm Therapeutics, Merck, Mundipharma, Novartis, Novocure, Nuvation Bio, Prelude Therapeutics, QED Therapeutics, Sapience, Vascular Biogenics, VBI Vaccines, and Voyager. PB is an employee of Novartis and reports stock ownership in Novartis and GlaxoSmithKline. PI is an employee of Novartis and reports stock ownership in Novartis. VS reports grants or research support from AbbVie, Agensys, Alfasigma, Altum, Amgen, Bayer, Berghealth, Blueprint Medicines, Boston Biomedical, Boston Pharmaceuticals, D3 Pharma, Dragonfly Therapeutics, Exelixis, Fujifilm, Idera Pharmaceuticals, Incyte, Inhibrx, Loxo Oncology, MedImmune, MultiVir, National Comprehensive Cancer Network, National Cancer Institute-Cancer Therapy Evaluation Program, Novartis, Pfizer, PharmaMar, Takeda, The University of Texas MD Anderson Cancer Center, and Turning Point Therapeutics; has an advisory or board member role in Eli Lilly, Helsinn, Incyte, Loxo Oncology, MedImmune, Novartis, QED Therapeutics, and R-Pharma US; is an Andrew Sabin Family Foundation Fellow at The University of Texas MD Anderson Cancer Center; receives financial support from The Jacquelyn A Brady Fund and the US National Institutes of Health (grant R01CA242845); and is affiliated with The University of Texas MD Anderson Cancer Center, which receives the US National Institutes of Health support grant (P30 CA016672). We thank Sharol Janice Rodrigues (Novartis Healthcare) for providing medical writing and editorial support, which was funded by Novartis Pharmaceuticals in accordance with Good Publication Practice guidelines (http://www.ismpp.org/gpp3).