Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Aug 1;1(1):4.
doi: 10.1186/s42836-019-0003-7.

Reducing the risk of infection after total joint arthroplasty: preoperative optimization

Brielle Antonelli  1 , Antonia F Chen  2
Affiliations
Review

Reducing the risk of infection after total joint arthroplasty: preoperative optimization

Brielle Antonelli et al. Arthroplasty. .

Abstract

Total joint arthroplasty (TJA) is one of the most commonly performed procedures in orthopedic surgery, and as the demand for TJA increases over time, the number of concurrent complications such as surgical infection will also increase. There are multiple risk factors that independently increase the risk of surgical site infection (SSI) and periprosthetic joint infection (PJI) after surgery. These modifiable risk factors can be identified in preoperative clinic screening visits that gives physicians the opportunity to provide specific intervention that can decrease patient infection risk. The risk factors that are known to significantly increase the risk of PJI and/or SSI include MSSA/MRSA colonization, rheumatoid arthritis, cardiovascular and renal disease, obesity, diabetes mellitus, hyperglycemia, anemia, malnutrition, tobacco use, alcohol consumption, depression, and anxiety. Patients who present with one or more of these risk factors require intervention with a multidisciplinary approach including patient education, counseling, and follow-up. Preoperative patient optimization for high risk TJA patients can significantly decrease PJI and SSI risk while improving surgical outcomes and patient care.

PubMed Disclaimer

Conflict of interest statement

One of the authors has competing interests that are not relevant to the topics of this article. The other author declares that they have no competing interests.

Figures

Fig. 1
Fig. 1
Methicillin sensitive and resistant Staphylococcus aureus screening regimen
See this image and copyright information in PMC

References

    1. Kurtz S, Ong K, Lau E, Mowat F, Halpern M. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg. 2007;89(4):780–785. - PubMed
    1. Pruzansky JS, Bronson MJ, Grelsamer RP, Strauss E, Moucha CS. Prevalence of modifiable surgical site infection risk factors in hip and knee joint arthroplasty patients at an urban academic hospital. J Arthroplast. 2014;29(2):272–276. doi: 10.1016/j.arth.2013.06.019. - DOI - PubMed
    1. Marmor S, Kerroumi Y. Patient-specific risk factors for infection in arthroplasty procedure. Orthop Traumatol Surg Res. 2016;102(1, Supplement):S113–S119. doi: 10.1016/j.otsr.2015.05.012. - DOI - PubMed
    1. Lee J, Singletary R, Schmader K, Anderson DJ, Bolognesi M, Kaye KS. Surgical site infection in the elderly following orthopaedic surgery: risk factors and outcomes. J Bone Joint Surg. 2006;88(8):1705–1712. doi: 10.2106/JBJS.E.01156. - DOI - PubMed
    1. Pulido L, Ghanem E, Joshi A, Purtill JJ, Parvizi J. Periprosthetic joint infection: the incidence, timing, and predisposing factors. Clin Orthop Relat Res. 2008;466(7):1710–1715. doi: 10.1007/s11999-008-0209-4. - DOI - PMC - PubMed

LinkOut - more resources