Pseudosubarachnoid hemorrhage

Abstract

Background: Imaging findings postcardiac arrest can influence medical decisions and have impact on discussions with caregivers.

Case description: A 44-year-old female presented to the emergency department and later had an in hospital cardiac arrest. Return of spontaneous circulation was obtained and the patient was taken for imaging which was read as diffuse bilateral subarachnoid hemorrhage. Magnetic resonance imaging of the brain performed later showed no evidence of subarachnoid hemorrhage nor was it seen later on autopsy.

Conclusion: Pseudosubarachnoid hemorrhage can be seen in patients with diffuse cerebral edema, often in the setting of either hypercarbia or severe acute diffuse injury.

Keywords: Neurocritical care; Pseudosubarachnoid hemorrhage; Subarachnoid hemorrhage.

Figure 1:

Careful review of the computed tomography images reveals hyperdense appearance of the Sylvian and perimesencephalic vasculature as well as the tentorial leaflets. Note that the suprasellar cistern is not filled with hyperdensity nor is there hyperdensity in the sulci or layering of blood over the tentorium as would be evident with subarachnoid hemorrhage. Most importantly, one should note the loss of gray/white matter differentiation in this 44-year-old patient. The midbrain is low in density, the cisternal spaces are reduced in size, and the cerebellum demonstrates no gray/white matter differentiation. The relatively hyperdense appearance of vessels within the Sylvian and perimesencephalic cisterns, the reduced size of the basal cisterns, and the parenchymal hypodensity are indicative of diffuse anoxic injury – not subarachnoid hemorrhage.

Figure 2:

Magnetic resonance imaging – hyperacute protocol (susceptibility-weighted imaging, fluid-attenuation inversion recovery [FLAIR], diffusion-weighted imaging [DWI], and apparent diffusion coefficient [ADC] sequence). (1) FLAIR images demonstrate no evidence of abnormal signal within the subarachnoid fluid spaces and no flow-related enhancement. (2 and 3) Diffuse supratentorial restricted diffusion is noted with involvement of the deep nuclei (caudate, lentiform, and pulvinar) on DWI and ADC sequences. (4) Susceptibility-weighted imaging image demonstrates no blooming artifact or low signal intensity within the basal cisterns or sulci as would be identified with subarachnoid hemorrhage.